Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)-

Base Information

Chemical Name:Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)-
CAS No.:77294-04-3
Molecular Formula:C23H26FN3O
Molecular Weight:379.4704
Hs Code.:
DSSTox Substance ID:DTXSID70998541

Synonyms:BRN 4210083;77294-04-3;Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)-;C23H26FN3O;DTXSID70998541;LS-127737;2-[3-(4-Fluorophenoxy)propyl]-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indole

Suppliers and Price of Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)-

Chemical Property:

Boiling Point:573.4°Cat760mmHg
Flash Point:300.6°C
Density:1.28g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:379.20599062
Heavy Atom Count:28
Complexity:512

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CC3=C(CC2CN1CCCOC4=CC=C(C=C4)F)C5=CC=CC=C5N3

Technology Process of Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)-

There total 3 articles about Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 1,2,3,4,6,7,12,12a-octahydro-2-(3-(4-fluorophenoxy)propyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1716-42-3
1-(3-chloropropoxy)-4-fluorobenzene

: 55344-28-0
1,2,3,4,6,7,12,12a-octahydropyrazino<2',1':6,1>pyrido<3,4-b>indole

: 77294-04-3
2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole

Guidance literature:: With sodium carbonate; sodium iodide; In N,N-dimethyl-formamide; at 80 ℃; for 60h;

Reference yield: 75.0%

: 55344-28-0
1,2,3,4,6,7,12,12a-octahydropyrazino<2',1':6,1>pyrido<3,4-b>indole

: 77294-04-3
2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole

Guidance literature:: With sodium carbonate; sodium iodide; In N,N-dimethyl-formamide;

Reference yield:

: 371-41-5
4-Fluorophenol

: 77294-04-3
2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / 30percent aq. NaOH / 6 h / Heating

2: 93 percent / NaI, Na₂CO₃ / dimethylformamide / 60 h / 80 °C

With sodium hydroxide; sodium carbonate; sodium iodide; In N,N-dimethyl-formamide;