dibenzo[b,f]thiepine-3-carboxylic acid 5,5-dioxide

Base Information

Chemical Name:dibenzo[b,f]thiepine-3-carboxylic acid 5,5-dioxide
CAS No.:71474-64-1
Molecular Formula:C15H10O4S
Molecular Weight:286.3025
Hs Code.:

Synonyms:dibenzo[b,f]thiepine-3-carboxylic acid 5,5-dioxide;Dibenzo(b,f)thiepin-3-carboxylic acid,5,5-dioxide;

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of dibenzo[b,f]thiepine-3-carboxylic acid 5,5-dioxide

Chemical Property:

Vapor Pressure:9.43E-13mmHg at 25°C
Boiling Point:545.9°Cat760mmHg
Flash Point:284°C
PSA：79.82000
Density:1.459g/cm³
LogP:3.78220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of dibenzo[b,f]thiepine-3-carboxylic acid 5,5-dioxide

There total 9 articles about dibenzo[b,f]thiepine-3-carboxylic acid 5,5-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 71474-60-7
dibenzothiepin-3-carboxylic acid

: 71474-64-1
dibenzothiepin-3-carboxylic acid 5,5-dioxide

Guidance literature:: With sodium perborate; In acetic acid; at 60 - 115 ℃; for 1h;
DOI:10.1002/jhet.5570230513

Reference yield:

: 71474-63-0
3-cyano-dibenzo[b,f]thiepin-5,5-dioxide

: 71474-64-1
dibenzothiepin-3-carboxylic acid 5,5-dioxide

Guidance literature:: With sodium hydroxide; In ethanol;

Reference yield:

: 2458-12-0
3-amino-p-toluic acid

: 71474-64-1
dibenzothiepin-3-carboxylic acid 5,5-dioxide

Guidance literature:: Multi-step reaction with 7 steps

1: 1) sodium nitrite, aq. HCl 2) KI, CuI / 1) under 0 deg C 2) water, 2 h reflux

2: 100 percent / NaOH, CuI / H₂O / 8 h / Heating

3: 99 percent / 1) lithium diisopropylamide / tetrahydrofuran; various solvent(s) / 1) -5 to -15 deg C, 40 min. 2) warming to 10 deg C, 3 h

4: 98 percent / polyphosphoric acid, water / 0.5 h / 140 °C

5: 97 percent / NaOH, NaBH₄ / ethanol; H₂O / 2 h / Ambient temperature

6: 86 percent / conc. H₂SO₄ / acetic acid / 1 h / 55 - 75 °C

7: 95 percent / sodium perborate tetrahydrate / acetic acid / 1 h / 60 - 115 °C

With hydrogenchloride; sodium perborate; sodium hydroxide; sodium tetrahydroborate; copper(l) iodide; PPA; sulfuric acid; water; potassium iodide; lithium diisopropyl amide; sodium nitrite; In tetrahydrofuran; ethanol; water; acetic acid;
DOI:10.1002/jhet.5570230513