Chemical Property of Leonurine
Chemical Property:
- Appearance/Colour:brown powder
- Melting Point:191-193oC
- Boiling Point:531.6 °C at 760 mmHg
- PKA:8.26±0.25(Predicted)
- Flash Point:275.3 °C
- PSA：126.89000
- Density:1.29 g/cm3
- LogP:2.02040
- Storage Temp.:2-8°C
- Solubility.:DMSO: soluble2mg/mL, clear (warmed)
- XLogP3:0.5
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:9
- Exact Mass:311.14812078
- Heavy Atom Count:22
- Complexity:360
- Purity/Quality:
-
99% *data from raw suppliers
Leonurine *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:COC1=CC(=CC(=C1O)OC)C(=O)OCCCCN=C(N)N
-
Description
An amorphous alkaloid, leonurine has been obtained from the leaves of Leonurus
sibiricus L. and is characterized as the crystalline hydrochloride hydra te, m.p.
19l-4°C. Hydrolysis yields syringic acid and Q-hydroxybutylguanidine. The
total synthesis of the alkaloid has been achieved, confirming the above structure.
-
Uses
Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases.
