3-phenoxy-N-methylmorphinan

Base Information

• Chemical Name: 3-phenoxy-N-methylmorphinan
• CAS No.: 67562-76-9
• Molecular Formula: C23H27NO
• Molecular Weight: 333.4666
• Mol file: 67562-76-9.mol

Synonyms:(+-)-3-phenoxy-N-methylmorphinan;(--)-3-phenoxy-N-methylmorphinan;3-phenoxy-N-methylmorphinan;(+)-3-phenoxy-N-methylmorphinan;

Chemical Property of 3-phenoxy-N-methylmorphinan

Chemical Property:

• Vapor Pressure: 1.81E-08mmHg at 25°C
• Boiling Point: 455.1°Cat760mmHg
• Flash Point: 132.8°C
• PSA: 12.47000
• Density: 1.16g/cm³
• LogP: 5.10500

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-phenoxy-N-methylmorphinan

There total 4 articles about 3-phenoxy-N-methylmorphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromobenzene (108-86-1,52753-63-6) + Levorphanol (77-07-6,125-73-5,297-90-5,2616-02-6,59684-82-1) → (-)-3-phenoxy-N-methylmorphinan (67562-76-9)

Guidance literature:

With pyridine; copper; potassium carbonate; for 192h; Heating;

DOI:10.1021/jm00375a024

Reference yield:

(+/-)-3-phenyl-N-formylmorphinan → (-)-3-phenoxy-N-methylmorphinan (67562-76-9)

Guidance literature:

In tetrahydrofuran; water; ethyl acetate;

Reference yield:

→ (-)-3-phenoxy-N-methylmorphinan (67562-76-9) + (-)-3-phenoxy-N-methylmorphinan d-tartrate (74569-98-5)

Guidance literature:

upstream raw materials:

bromobenzene

Levorphanol

Downstream raw materials:

(-)-3-Phenoxy-17-cyclopropylcarbonylmorphinan