2-hydroxycyclohexyl propanoate

Base Information

Chemical Name:2-hydroxycyclohexyl propanoate
CAS No.:7402-18-8
Molecular Formula:C₉H₁₆O₃
Molecular Weight:172.224
Hs Code.:

Synonyms:1,2-Cyclohexanediol, 1-propanoate;

Suppliers and Price of 2-hydroxycyclohexyl propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of 2-hydroxycyclohexyl propanoate

Chemical Property:

Vapor Pressure:0.00632mmHg at 25°C
Refractive Index:1.471
Boiling Point:241.098 °C at 760 mmHg
Flash Point:94.087 °C
Density:1.07 g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-hydroxycyclohexyl propanoate

There total 9 articles about 2-hydroxycyclohexyl propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1460-57-7
trans-1,2-cyclohexandiol

: 802294-64-0,79-09-4
propionic acid

: 57794-08-8
(1S,2S)-trans-1,2-Cyclohexanediol

: 1227311-62-7
cyclohexane-1,2-diol

: 7402-18-8,23720-85-6
cyclohexane-1,2-diol

Guidance literature:: With Boc-L-(?-Me)-His-AGly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide; In toluene; at 0 ℃; for 15h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c001075h

Reference yield:

: 1373216-32-0
tris(4-isopropylphenyl)silyl chloride

: trans-2-hydroxycyclohexyl propionate

: 1227311-62-7
cyclohexane-1,2-diol

: 7402-18-8,23720-85-6
cyclohexane-1,2-diol

: C₃₆H₄₈O₃Si

: C₃₆H₄₈O₃Si

Guidance literature:: trans-2-hydroxycyclohexyl propionate; With (S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at -78 ℃; for 0.5h; Molecular sieve; Inert atmosphere; Sealed tube;

tris(4-isopropylphenyl)silyl chloride; In tetrahydrofuran; at -78 ℃; for 48h; Molecular sieve; Inert atmosphere; Sealed tube;
DOI:10.1002/ejoc.201900754

Reference yield:

: 1460-57-7
trans-1,2-cyclohexandiol

: 7402-18-8,23720-85-6
cyclohexane-1,2-diol

Guidance literature:: Multi-step reaction with 2 steps

1.1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

1.2: 4 h / 20 °C / Inert atmosphere

2.1: (S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C / Molecular sieve; Inert atmosphere; Sealed tube

2.2: 48 h / -78 °C / Molecular sieve; Inert atmosphere; Sealed tube

With dmap; (S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1002/ejoc.201900754