Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate
CAS No.:122860-33-7
Molecular Formula:C14H19NO3
Molecular Weight:249.31
Hs Code.:2933399090
European Community (EC) Number:675-939-8
DSSTox Substance ID:DTXSID90353037
Wikidata:Q72516214
Mol file:122860-33-7.mol

Synonyms:122860-33-7;benzyl 4-(hydroxymethyl)piperidine-1-carboxylate;1-Cbz-4-hydroxymethylpiperidine;N-Cbz-4-(hydroxymethyl)piperidine;n-cbz-4-piperidinemethanol;1-n-cbz-4-hydroxymethyl-piperidine;1-cbz-4-hydroxymethyl-piperidine;1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, phenylmethyl ester;4-Hydroxymethyl-Piperidine-1-Carboxylic Acid Benzyl Ester;benzyl 4-(hydroxymethyl)tetrahydro-1(2h)-pyridinecarboxylate;MFCD02094490;1-N-Cbz-hydroxymethyl-piperidine;4-hydroxymethylpiperidine-1-carboxylic acid benzyl ester;1-cbz-4-hydroxy methyl piperidine;1-n-cbz-4-hydroxymethylpiperidine;N-(Benzyloxycarbonyl)-4-(Hydroxymethyl)piperidine;z-isonicot(h6)-ol;SCHEMBL458805;DTXSID90353037;LINIORCIRVAZSM-UHFFFAOYSA-N;1-cbz-4-(hydroxymethyl)piperidine;AKOS009158309;AC-2793;CS-W002888;PB23274;N-benzyloxycarbonylpiperidine-4-methanol;AS-18688;SY002934;1-(Benzyloxycarbonyl)-4-piperidinemethanol;1-benzyloxycarbonyl-4-hydroxymethylpiperidine;A2596;AM20020316;FT-0622804;n-benzyloxycarbonyl-4-hydroxymethylpiperidine;benzyl4-(hydroxymethyl)piperidine-1-carboxylate;EN300-189852;N-Benzyloxycarbonyl-4-(hydroxymethyl)piperidine;benzyl 4-(hydroxymethyl)-1-piperidinecarboxylate;1-(benzyloxycarbonyl)-4-(hydroxymethyl)piperidine;A1-00413;4-Hydroxymethyl-piperidine-l-carboxylic acid benzyl ester;phenylmethyl 4-(hydroxymethyl)-1-piperidine carboxylate;Z635047520

Suppliers and Price of Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-N-Cbz-hydroxymethyl-piperidine
5g
$ 70.00

TRC
1-N-Cbz-hydroxymethyl-piperidine
1g
$ 55.00

Synthonix
1-Cbz-4-hydroxymethylpiperidine 95+%
25g
$ 40.00

SynQuest Laboratories
Benzyl 4-(hydroxymethyl)tetrahydro-1(2H)-pyridinecarboxylate
5 g
$ 150.00

Matrix Scientific
Benzyl 4-(Hydroxymethyl)piperidine-1-carboxylate 97%
25g
$ 128.00

Matrix Scientific
Benzyl 4-(Hydroxymethyl)piperidine-1-carboxylate 97%
100g
$ 398.00

J&W Pharmlab
1-Cbz-4-hydroxymethyl-piperidine 97%
25g
$ 998.00

J&W Pharmlab
1-Cbz-4-hydroxymethyl-piperidine 97%
5g
$ 298.00

Crysdot
Benzyl4-(hydroxymethyl)piperidine-1-carboxylate 97%
100g
$ 143.00

ChemScene
Benzyl4-(hydroxymethyl)piperidine-1-carboxylate ≥97.0%
100g
$ 104.00

Total 81 raw suppliers

Chemical Property of Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

Chemical Property:

Appearance/Colour:Brown Liquid
Vapor Pressure:5.4E-07mmHg at 25°C
Refractive Index:1.549
Boiling Point:396.374 °C at 760 mmHg
PKA:14.94±0.10(Predicted)
Flash Point:193.52 °C
PSA：49.77000
Density:1.163 g/cm³
LogP:1.96540
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:256

Purity/Quality:

99%, ^*data from raw suppliers

1-N-Cbz-hydroxymethyl-piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1CO)C(=O)OCC2=CC=CC=C2
Uses 1-N-Cbz-hydroxymethyl-piperidine is an intermediate used in the synthesis of benzoyloxyethylpiperidinylmethylamine as fluorescent antagonists for human 5-HT4 receptors. It is also used to prepare diaminobutane derivatives as potent Ca2+-Permeable AMPA receptor antagonists.

Technology Process of Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

There total 12 articles about Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%