3-[(2-Chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole

Base Information

Chemical Name:3-[(2-Chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole
CAS No.:6132-92-9
Molecular Formula:C17H14ClFN2O2
Molecular Weight:332.7567
Hs Code.:
DSSTox Substance ID:DTXSID30361974
Wikidata:Q82144640

Synonyms:3-[(2-chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole;6132-92-9;CBMicro_007916;Oprea1_147232;DTXSID30361974;SMSF0014675;BIM-0007957.P001

Suppliers and Price of 3-[(2-Chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-[(2-Chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole

Chemical Property:

Vapor Pressure:1.73E-08mmHg at 25°C
Boiling Point:468.1°Cat760mmHg
Flash Point:236.9°C
Density:1.279g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:332.0727835
Heavy Atom Count:23
Complexity:369

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)C2=NC(=NO2)CC3=C(C=CC=C3Cl)F

Technology Process of 3-[(2-Chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole

There total 7 articles about 3-[(2-Chloro-6-fluorophenyl)methyl]-5-(4-ethoxyphenyl)-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 6132-90-7
3-methoxy-11H-benzo[a]carbazole

: 6132-92-9
3-hydroxybenzo[a]carbazole

Guidance literature:: With pyridine hydrochloride; Heating;
DOI:10.1016/j.tet.2004.12.055

Reference yield:

: 6132-87-2
6,11-dihydro-8-methoxy-5H-benzo carbazole

: 6132-92-9
3-hydroxybenzo[a]carbazole

Guidance literature:: Multi-step reaction with 2 steps

1: tetrachloro-1,4-benzoquinone / xylene / 2 h / Heating

2: 94 percent / pyridine hydrochloride / Heating

With pyridine hydrochloride; chloranil; In xylene;
DOI:10.1016/j.tet.2004.12.055

Reference yield:

: 1078-19-9
6-methoxy-3,4-dihydro-1(2H)-naphthalenone

: 6132-92-9
3-hydroxybenzo[a]carbazole

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / ethanol / 1 h / Heating

2: tetrachloro-1,4-benzoquinone / xylene / 2 h / Heating

3: 94 percent / pyridine hydrochloride / Heating

With pyridine hydrochloride; chloranil; acetic acid; In ethanol; xylene;
DOI:10.1016/j.tet.2004.12.055