2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline

Base Information

Chemical Name:2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline
CAS No.:50510-13-9
Molecular Formula:C11H14N2O2S
Molecular Weight:238.31
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10964740
Nikkaji Number:J78.686A
Mol file:50510-13-9.mol

Synonyms:50510-13-9;BRN 0987363;2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline;2-Oxazoline, 2-amino-5-((p-methoxyphenyl)thiomethyl)-;2-Oxazolamine, 4,5-dihydro-5-((p-methoxyphenyl)thiomethyl)-;2-Amino-5-[(p-methoxyphenyl)thiomethyl]-2-oxazoline;2-Oxazolamine, 4,5-dihydro-5-[[(4-methoxyphenyl)thio]methyl]-;DTXSID10964740;LS-100719;5-{[(4-Methoxyphenyl)sulfanyl]methyl}-1,3-oxazolidin-2-imine

Suppliers and Price of 2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-AMINO-5-[(P-METHOXYPHENYL)THIOMETHYL]-2-OXAZOLINE 95.00%
5MG
$ 499.36

Total 4 raw suppliers

Chemical Property of 2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline

Chemical Property:

Vapor Pressure:1.37E-06mmHg at 25°C
Boiling Point:399.4°C at 760 mmHg
PKA:8.52±0.10(Predicted)
Flash Point:195.3°C
PSA：79.64000
Density:1.31g/cm³
LogP:2.13900
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:238.07759887
Heavy Atom Count:16
Complexity:252

Purity/Quality:

99% ^*data from raw suppliers

2-AMINO-5-[(P-METHOXYPHENYL)THIOMETHYL]-2-OXAZOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)SCC2CN=C(O2)N

Technology Process of 2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline

There total 3 articles about 2-Amino-5-((p-methoxyphenyl)thiomethyl)-2-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 557-11-9
allylurea

: 1950-65-8
4-methoxybenzenesulfenyl chloride

: 50510-13-9
5-(4-methoxy-phenylsulfanylmethyl)-4,5-dihydro-oxazol-2-ylamine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; for 0.5h; Ambient temperature;
DOI:10.1007/BF00807436

Reference yield:

: 24920-60-3
(4-methoxy-phenylsulfanylmethyl)-oxirane

: 50510-13-9
5-(4-methoxy-phenylsulfanylmethyl)-4,5-dihydro-oxazol-2-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NH₃

2: NaOAc / methanol

With ammonium hydroxide; sodium acetate; In methanol;
DOI:10.1021/jm00263a022