8-chloro-6-(2-chlorophenyl)-4H-imidazo(1,5-a)(1,4)-benzodiazepine-3-carboxamide

Base Information

Chemical Name:8-chloro-6-(2-chlorophenyl)-4H-imidazo(1,5-a)(1,4)-benzodiazepine-3-carboxamide
CAS No.:63176-94-3
Molecular Formula:C18H12Cl2N4O
Molecular Weight:371.2201
Hs Code.:

Synonyms:8-chloro-6-(2-chlorophenyl)-4H-imidazo<1,5-a><1,4>benzodiazepine-3-carboxamide;CCIBC;8-chloro-6-(2-chloro-phenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid amide;RO 21 8384;

Suppliers and Price of 8-chloro-6-(2-chlorophenyl)-4H-imidazo(1,5-a)(1,4)-benzodiazepine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 8-chloro-6-(2-chlorophenyl)-4H-imidazo(1,5-a)(1,4)-benzodiazepine-3-carboxamide

Chemical Property:

Vapor Pressure:2.68E-14mmHg at 25°C
Boiling Point:598.8°Cat760mmHg
Flash Point:315.9°C
PSA：74.26000
Density:1.53g/cm³
LogP:3.94880

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-chloro-6-(2-chlorophenyl)-4H-imidazo(1,5-a)(1,4)-benzodiazepine-3-carboxamide

There total 4 articles about 8-chloro-6-(2-chlorophenyl)-4H-imidazo(1,5-a)(1,4)-benzodiazepine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 109774-27-8
8-chloro-6-(2-chlorophenyl)-4H-imidazo<1,5-a><1,4>benzodiazepine-3-carbonitrile

: 63176-94-3
8-chloro-6-(2-chlorophenyl)-4H-imidazo<1,5-a><1,4>benzodiazepine-3-carboxamide

Guidance literature:: With sulfuric acid; for 1.5h; Ambient temperature;
DOI:10.1002/jhet.5570230509

Reference yield:

: 63176-91-0
8-chloro-6-(2-chloro-phenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid methyl ester

: 63176-94-3
8-chloro-6-(2-chlorophenyl)-4H-imidazo<1,5-a><1,4>benzodiazepine-3-carboxamide

Guidance literature:: With ammonia; In methanol; dichloromethane;

Reference yield:

: 109774-52-9
8-chloro-6-(2-chlorophenyl)-5,6-dihydro-4H-imidazo<1,5-a><1,4>benzodiazepine-3-carbonitrile

: 63176-94-3
8-chloro-6-(2-chlorophenyl)-4H-imidazo<1,5-a><1,4>benzodiazepine-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 33 percent / toluene / 24 h / Heating

2: 88 percent / concentrated H₂SO₄ / 1.5 h / Ambient temperature

With sulfuric acid; In toluene;
DOI:10.1002/jhet.5570230509