(Z)-3-(2-hydroxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile

Base Information

• Chemical Name: (Z)-3-(2-hydroxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile
• CAS No.: 14121-93-8
• Molecular Formula: C₁₅H₁₀N₂O₃
• Molecular Weight: 266.256
• NSC Number: 62435
• Mol file: 14121-93-8.mol

Synonyms:NSC62435;14121-93-8;NSC-62435;AKOS000296873

Chemical Property of (Z)-3-(2-hydroxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile

Chemical Property:

• Vapor Pressure: 4.03E-08mmHg at 25°C
• Boiling Point: 433.5°Cat760mmHg
• Flash Point: 216°C
• Density: 1.357g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 266.06914219
• Heavy Atom Count: 20
• Complexity: 424

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C=C(C#N)C2=CC=C(C=C2)[N+](=O)[O-])O
• Isomeric SMILES: C1=CC=C(C(=C1)/C=C(\C#N)/C2=CC=C(C=C2)[N+](=O)[O-])O

Technology Process of (Z)-3-(2-hydroxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile

There total 1 articles about (Z)-3-(2-hydroxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9) + salicylaldehyde (90-02-8) → 2-(4-nitro-phenyl)-3c-(2-hydroxy-phenyl)-acrylonitrile (14121-93-8)

Guidance literature:

With piperidine; ethanol;

Reference yield:

2-Hydroxy-α-<4-nitro-phenyl>-zimtsaeure-nitril (14121-93-8) → 3-(4-nitrophenyl)coumarin (2555-25-1)

Guidance literature:

With acetic acid;

DOI:10.1021/jo01095a611

Reference yield:

2-(4-nitro-phenyl)-3c-(2-hydroxy-phenyl)-acrylonitrile (14121-93-8) + acetic acid (64-19-7,77671-22-8) → 3-(4-nitrophenyl)coumarin (2555-25-1)

Guidance literature:

DOI:10.1007/BF00904443 DOI:10.1021/jo01095a611

upstream raw materials:

4-Nitrophenylacetonitrile

salicylaldehyde

Downstream raw materials:

3-(4-nitrophenyl)coumarin