(R)-Viloxazine

Base Information

Chemical Name:(R)-Viloxazine
CAS No.:52730-45-7
Molecular Formula:C₁₃H₁₉NO₃
Molecular Weight:237.299
Hs Code.:
UNII:HP6E97INCN
ChEMBL ID:CHEMBL250052
Nikkaji Number:J2.203.478B

Synonyms:(R)-Viloxazine;(+)-Viloxazine;Viloxazine, (R)-;52730-45-7;HP6E97INCN;(R)-2-(o-Ethoxyphenoxymethyl)morpholine;(2R)-2-[(2-ethoxyphenoxy)methyl]morpholine;Morpholine, 2-((2-ethoxyphenoxy)methyl)-, (R)-;Morpholine, 2-((2-ethoxyphenoxy)methyl)-, (2R)-;UNII-HP6E97INCN;CHEMBL250052;SCHEMBL2524727

Suppliers and Price of (R)-Viloxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-Viloxazine

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:237.13649347
Heavy Atom Count:17
Complexity:213

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=CC=CC=C1OCC2CNCCO2
Isomeric SMILES:CCOC1=CC=CC=C1OC[C@H]2CNCCO2

Technology Process of (R)-Viloxazine

There total 2 articles about (R)-Viloxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56287-69-5
(R)-2-(2-ethoxy-phenoxymethyl)-4-isopropyl-morpholine

: 52730-45-7
(R)-2-(2-ethoxy-phenoxymethyl)-morpholine

Guidance literature:: Multistep reaction; (i) PhOCOCl, benzene, (ii) KOH, EtOH;
DOI:10.1021/jm00230a021

Reference yield:

: 27480-08-6
1-(2-ethoxy-phenoxy)-3-isopropylamino-propan-2-ol

: 52730-45-7
(R)-2-(2-ethoxy-phenoxymethyl)-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: (i) Et₃N, Et₂O, (ii) NaOMe, MeOH, (iii) LiAlH₄, Et₂O

2: (i) PhOCOCl, benzene, (ii) KOH, EtOH

DOI:10.1021/jm00230a021