2-Chloro-6-benzyloxybenzonitrile

Base Information

Chemical Name:2-Chloro-6-benzyloxybenzonitrile
CAS No.:92161-40-5
Molecular Formula:C14H10 Cl N O
Molecular Weight:243.692
Hs Code.:
European Community (EC) Number:295-901-0
DSSTox Substance ID:DTXSID00238907
Nikkaji Number:J333.375B
Wikidata:Q83121249
Mol file:92161-40-5.mol

Synonyms:2-Chloro-6-benzyloxybenzonitrile;92161-40-5;2-(Benzyloxy)-6-chlorobenzonitrile;EINECS 295-901-0;2-chloro-6-phenylmethoxybenzonitrile;Oprea1_225093;DTXSID00238907;Benzonitrile, 2-benzyloxy-6-chloro-;2-(Benzyloxy)-6-chlorobenzonitrile #;AKOS009096409;2-Chloro-6-(phenylmethoxy)benzonitrile;Benzonitrile, 2-chloro-6-(phenylmethoxy)-

Suppliers and Price of 2-Chloro-6-benzyloxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-6-BENZYLOXYBENZONITRILE 95.00%
5MG
$ 502.33

Total 5 raw suppliers

Chemical Property of 2-Chloro-6-benzyloxybenzonitrile

Chemical Property:

Vapor Pressure:6.43E-07mmHg at 25°C
Boiling Point:409.6°Cat760mmHg
Flash Point:201.5°C
PSA：33.02000
Density:1.25g/cm³
LogP:3.79068
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:243.0450916
Heavy Atom Count:17
Complexity:279

Purity/Quality:

99% ^*data from raw suppliers

2-CHLORO-6-BENZYLOXYBENZONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C(=CC=C2)Cl)C#N

Technology Process of 2-Chloro-6-benzyloxybenzonitrile

There total 1 articles about 2-Chloro-6-benzyloxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 92161-40-5
2-benzyloxy-6-chlorobenzonitrile

Guidance literature:: Benzonitril (I), Benzylalkohol, KOH;

Reference yield: 66.0%

: 92161-40-5
2-benzyloxy-6-chlorobenzonitrile

: 89999-90-6
3-chloro-2-cyanophenol

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 25 ℃; for 24h;
DOI:10.1021/jm034248l

Reference yield:

: 92161-40-5
2-benzyloxy-6-chlorobenzonitrile

: 201467-03-0
6-chloro-2-hydroxy-3-nitrobenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / TFA / CH₂Cl₂

2: 27 percent / NaNO₃; NaNO₂; H₂SO₄ / CH₂Cl₂

With sodium nitrate; sulfuric acid; trifluoroacetic acid; sodium nitrite; In dichloromethane;
DOI:10.1016/j.bmcl.2004.06.097