Urea, 1-(2-chloroethyl)-1-nitroso-3-p-tolyl-

Base Information

• Chemical Name: Urea, 1-(2-chloroethyl)-1-nitroso-3-p-tolyl-
• CAS No.: 14009-34-8
• Molecular Formula: C₁₀H₁₂ClN₃O₂
• Molecular Weight: 241.677
• NSC Number: 102869
• DSSTox Substance ID: DTXSID10930703
• Wikidata: Q82906116
• Mol file: 14009-34-8.mol

Synonyms:Urea,;Urea, 1-(2-chloroethyl)-1-nitroso-3-p-tolyl-;14009-34-8;NSC102869;NCIOpen2_007173;DTXSID10930703;NSC-102869;N-(2-Chloroethyl)-N'-(4-methylphenyl)-N-nitrosourea

Chemical Property of Urea, 1-(2-chloroethyl)-1-nitroso-3-p-tolyl-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.28g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 241.0618043
• Heavy Atom Count: 16
• Complexity: 242

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NC(=O)N(CCCl)N=O

Technology Process of Urea, 1-(2-chloroethyl)-1-nitroso-3-p-tolyl-

There total 2 articles about Urea, 1-(2-chloroethyl)-1-nitroso-3-p-tolyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4-methyl-<3-(2-chloroethyl)ureido>benzene (15145-35-4) → 4-methyl-<<3-(2-chloroethyl)3-nitroso>ureido>benzene (14009-34-8)

Guidance literature:

With formic acid; sodium nitrite;

DOI:10.1002/jps.2600770218

Reference yield:

p-toluidine (106-49-0,12221-03-3) → 4-methyl-<<3-(2-chloroethyl)3-nitroso>ureido>benzene (14009-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / 1,2-dimethoxy-ethane

2: 50 percent / NaNO₂, formic acid

With formic acid; sodium nitrite; In 1,2-dimethoxyethane;

DOI:10.1002/jps.2600770218

upstream raw materials:

4-methyl-<3-(2-chloroethyl)ureido>benzene

p-toluidine