1,2,3,4-Tetrahydro-6,7-dimethoxy-3-methylisoquinoline hydrochloride

Base Information

• Chemical Name: 1,2,3,4-Tetrahydro-6,7-dimethoxy-3-methylisoquinoline hydrochloride
• CAS No.: 6266-97-3
• Molecular Formula: C₁₂H₁₇NO₂*ClH
• Molecular Weight: 243.733
• Hs Code.: 29334990
• Mol file: 6266-97-3.mol

Synonyms:NSC 36661;1,2,3,4-Tetrahydro-6,7-dimethoxy-3-methylisoquinoline hydrochloride;ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-3-METHYL-, HYDROCHLORIDE;6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride;SCHEMBL5708777;LS-85916

Chemical Property of 1,2,3,4-Tetrahydro-6,7-dimethoxy-3-methylisoquinoline hydrochloride

Chemical Property:

• Appearance/Colour: almost white to light yellow fine cryst. powder
• Vapor Pressure: 0.000303mmHg at 25°C
• Melting Point: 250-252 °C
• Boiling Point: 321.2 °C at 760 mmHg
• Flash Point: 129.9 °C
• PSA: 30.49000
• LogP: 2.86880
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 243.1026065
• Heavy Atom Count: 16
• Complexity: 210

Purity/Quality:

98%min ^*data from raw suppliers

6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinolineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,N
• Statements: 36/37/38-50
• Safety Statements: 37/39-26-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2=CC(=C(C=C2C[NH2+]1)OC)OC.[Cl-]

Technology Process of 1,2,3,4-Tetrahydro-6,7-dimethoxy-3-methylisoquinoline hydrochloride

There total 1 articles about 1,2,3,4-Tetrahydro-6,7-dimethoxy-3-methylisoquinoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (6266-97-3)

Guidance literature:

With sulfuric acid; water; zinc;

DOI:10.1021/ja01859a050

Reference yield:

8-bromo-octanoic acid benzyloxy-amide (439940-89-3) + 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (6266-97-3) → 8-(6,7-dimethoxy-3-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-octanoic acid benzyloxyamide (439940-93-9)

Guidance literature:

potassium carbonate; N,N-dimethyl-formamide;

Downstream raw materials:

8-(6,7-dimethoxy-3-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-octanoic acid benzyloxyamide