1-Piperidinepropanol, 2-methyl-

Base Information

• Chemical Name: 1-Piperidinepropanol, 2-methyl-
• CAS No.: 94-88-2
• Molecular Formula: C9H19 N O
• Molecular Weight: 157.256
• Hs Code.: 2933399090
• NSC Number: 66276
• DSSTox Substance ID: DTXSID10883285
• Nikkaji Number: J182.109A
• Mol file: 94-88-2.mol

Synonyms:3-(2-methylpiperidin-1-yl)propan-1-ol;94-88-2;1-Piperidinepropanol, 2-methyl-;2-Methyl-1-piperidinepropanol;3-(2-methyl-piperidin-1-yl)-propan-1-ol;NSC66276;2-methylpiperidin-1-propanol;SCHEMBL2115516;DTXSID10883285;2-Methyl-1-piperidine-1-propanol;MFCD00023782;NSC-66276;3-(.alpha.-Methylpiperidino)propanol;AKOS009032730;3-(2-Methyl-1-piperidino)-1-propanol;CS-0252377;EN300-59989;Z168932308

Chemical Property of 1-Piperidinepropanol, 2-methyl-

Chemical Property:

• Vapor Pressure: 0.00413mmHg at 25°C
• Boiling Point: 247.6°C at 760 mmHg
• Flash Point: 103.8°C
• PSA: 23.47000
• Density: 0.929g/cm³
• LogP: 1.18110
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 157.146664230
• Heavy Atom Count: 11
• Complexity: 106

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-METHYL-1-PIPERIDINEPROPANOL Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCCCN1CCCO

Technology Process of 1-Piperidinepropanol, 2-methyl-

There total 2 articles about 1-Piperidinepropanol, 2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-chloro-3-hydroxypropane (627-30-5) + 2-Methylpiperidin (109-05-7,3000-79-1) → 2-methylpiperidine-1-propanol (94-88-2)

Guidance literature:

With potassium carbonate; In acetonitrile; for 20h; Heating;

DOI:10.1016/S0040-4020(01)80497-X

Reference yield:

2-Methylpiperidin (109-05-7,3000-79-1) + 1-bromo-3-propanol (627-18-9) → 2-methylpiperidine-1-propanol (94-88-2)

Guidance literature:

With potassium carbonate; at 140 ℃;

DOI:10.1021/ja01288a053

Reference yield: 45.0%

2-methylpiperidine-1-propanol (94-88-2) + 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carbonyl chloride (51950-71-1) → 3-(2-methyl-N-piperidino)-propyl 3-methylflavone-8-carboxylate

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 8h;

upstream raw materials:

1-chloro-3-hydroxypropane

2-Methylpiperidin

1-bromo-3-propanol

Downstream raw materials:

furan-2-carboxylic acid-[3-(2-methyl-piperidino)-propylester]; hydrochloride

thiophene-2-carboxylic acid-[3-(2-methyl-piperidino)-propylester]; hydrochloride

benzofuran-2-carboxylic acid-[3-(2-methyl-piperidino)-propylester]; hydrochloride

1-(2-methyl-piperidino)-3-p-toluoyloxy-propane; hydrochloride