ethyl 3-(benzylaMino)-3-Methylbutanoate

Base Information

• Chemical Name: ethyl 3-(benzylaMino)-3-Methylbutanoate
• CAS No.: 17945-54-9
• Molecular Formula: C14H21NO2
• Molecular Weight: 235.326
• Mol file: 17945-54-9.mol

Synonyms:3-Benzylamino-3-methyl-buttersaeureeethylester;ethyl 3-benzylamino-3-methylbutyrate;3-benzylamino-3-methylbutyric acid ethyl ester;

Chemical Property of ethyl 3-(benzylaMino)-3-Methylbutanoate

Chemical Property:

• Vapor Pressure: 0.000197mmHg at 25°C
• Boiling Point: 327.9°Cat760mmHg
• Flash Point: 152.1°C
• PSA: 38.33000
• Density: 1.007g/cm³
• LogP: 2.89890
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl3-(benzylamino)-3-methylbutanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 3-(benzylaMino)-3-Methylbutanoate

There total 1 articles about ethyl 3-(benzylaMino)-3-Methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

ethyl 3-methylbut-2-enoate (638-10-8) + benzylamine (100-46-9) → 3-benzylamino-3-methylbutyric acid ethyl ester (17945-54-9)

Guidance literature:

In ethanol; for 24h; Heating / reflux;

Reference yield: 65.0%

3-benzylamino-3-methylbutyric acid ethyl ester (17945-54-9) → 3-Benzylamino-3-methyl-butan-1-ol (17945-55-0)

Guidance literature:

3-benzylamino-3-methylbutyric acid ethyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 5.5h;

With water; In tetrahydrofuran; at 0 ℃;

Reference yield:

3-benzylamino-3-methylbutyric acid ethyl ester (17945-54-9) → 3-Dibenzylamino-3-methyl-butanol-(1) (17945-65-2)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / ethanol

2: LiAlH₄ / diethyl ether

With lithium aluminium tetrahydride; potassium carbonate; In diethyl ether; ethanol;

DOI:10.1021/jo01268a003

upstream raw materials:

ethyl 3-methylbut-2-enoate

benzylamine

Downstream raw materials:

3-Benzylamino-3-methyl-butan-1-ol

3-Dibenzylamino-3-methyl-buttersaeuree-ethylester

3-Dibenzylamino-3-methyl-butanol-⁽¹⁾

N-<4-Chlor-2-methyl-butyl-(2)>-benzylamin