2-(3-Fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one

Base Information

Chemical Name:2-(3-Fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one
CAS No.:6286-80-2
Molecular Formula:C11H11FN2O
Molecular Weight:206.2162
Hs Code.:
NSC Number:10363
DSSTox Substance ID:DTXSID00278863
Wikidata:Q82011037

Synonyms:6286-80-2;2-(3-fluorophenyl)-1,5-dimethylpyrazol-3-one;2-(3-fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one;NSC10363;DTXSID00278863;NSC 10363;NSC-10363

Suppliers and Price of 2-(3-Fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of 2-(3-Fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one

Chemical Property:

Vapor Pressure:0.0017mmHg at 25°C
Boiling Point:293.7°Cat760mmHg
Flash Point:131.4°C
Density:1.234g/cm³
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:206.08554114
Heavy Atom Count:15
Complexity:303

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=O)N(N1C)C2=CC(=CC=C2)F

Technology Process of 2-(3-Fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one

There total 2 articles about 2-(3-Fluorophenyl)-1,5-dimethyl-1,2-dihydro-3h-pyrazol-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 658-27-5
m-fluorophenylhydrazine

: 6286-80-2
2-(3-fluoro-phenyl)-1,5-dimethyl-1,2-dihydro-pyrazol-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / Heating

2: CaO / methanol

With calcium oxide; In methanol; acetonitrile;
DOI:10.1016/j.bmcl.2007.05.035

Reference yield:

: 55347-02-9
C₁₀H₉N₂OF

: 77-78-1
dimethyl sulfate

: 6286-80-2
2-(3-fluoro-phenyl)-1,5-dimethyl-1,2-dihydro-pyrazol-3-one

Guidance literature:: With calcium oxide; In methanol;
DOI:10.1016/j.bmcl.2007.05.035

Reference yield: 71.0%

: 941-69-5
N-phenyl-maleimide

: 6286-80-2
2-(3-fluoro-phenyl)-1,5-dimethyl-1,2-dihydro-pyrazol-3-one

: 3-(2-(3-fluorophenyl)-1,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-1H-pyrrole-2,5-dione

Guidance literature:: With copper(II) acetate monohydrate; palladium dichloride; In tert-Amyl alcohol; at 100 ℃; for 6h; regioselective reaction;
DOI:10.1039/d1ob00819f