2,3,5-Tri-o-acetyl-1,4-anhydro-1-(7-chloro-2h-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol

Base Information

• Chemical Name: 2,3,5-Tri-o-acetyl-1,4-anhydro-1-(7-chloro-2h-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol
• CAS No.: 33822-98-9
• Molecular Formula: C16H17ClN4O7
• Molecular Weight: 412.7818
• NSC Number: 109315
• DSSTox Substance ID: DTXSID10955411

Synonyms:33822-98-9;NSC109315;2,3,5-tri-o-acetyl-1,4-anhydro-1-(7-chloro-2h-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol;DTXSID10955411;NSC-109315

Chemical Property of 2,3,5-Tri-o-acetyl-1,4-anhydro-1-(7-chloro-2h-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.51g/cm³
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 8
• Exact Mass: 412.0785766
• Heavy Atom Count: 28
• Complexity: 624

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OCC1C(C(C(O1)C2=C3C(=NN2)C(=NC=N3)Cl)OC(=O)C)OC(=O)C

Technology Process of 2,3,5-Tri-o-acetyl-1,4-anhydro-1-(7-chloro-2h-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol

There total 3 articles about 2,3,5-Tri-o-acetyl-1,4-anhydro-1-(7-chloro-2h-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-pyrazolo<4,3-d>pyrimidin-7-on (13387-98-9) → 7-chloro-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazolo<4,3-d>pyrimidine (33822-98-9)

Guidance literature:

With trichlorophosphate; for 0.5h; Heating / reflux;

Reference yield:

formycin-B (13877-76-4,63347-44-4) → 7-chloro-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazolo<4,3-d>pyrimidine (33822-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Py / 5 h / 0 - 20 °C

2: POCl₃ / 0.5 h / Heating

With pyridine; trichlorophosphate;

DOI:10.1016/S0960-894X(99)00298-X

Reference yield:

3-(tri-O-acetyl-β-D-ribofuranosyl)-1(2),6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one → 7-chloro-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazolo<4,3-d>pyrimidine (33822-98-9)

Guidance literature:

With trichlorophosphate;

DOI:10.1039/j39710002443

upstream raw materials:

3-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-pyrazolo<4,3-d>pyrimidin-7-on

formycin-B

Downstream raw materials:

(1S)-1-(7-allylsulfanyl-1(2)H-pyrazolo[4,3-d]pyrimidin-3-yl)-D-1,4-anhydro-ribitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 33822-98-9 2,3,5-tri-O-acetyl-1,4-anhydro-1-(7-chloro-2H-pyrazolo[4,3-d]pyrimidin-3-yl)pentitol

Send

Send

Metric Ton KG G Pound L ML

Send

Send