16,17-Dihydro-11-methyl-15H-cyclopenta[a]phenanthren-17-ol

Base Information

• Chemical Name: 16,17-Dihydro-11-methyl-15H-cyclopenta[a]phenanthren-17-ol
• CAS No.: 40951-13-1
• Molecular Formula: C18H16O
• Molecular Weight: 248.34
• Mol file: 40951-13-1.mol

Synonyms:

Chemical Property of 16,17-Dihydro-11-methyl-15H-cyclopenta[a]phenanthren-17-ol

Chemical Property:

• Vapor Pressure: 1.01E-09mmHg at 25°C
• Refractive Index: 1.4700 (estimate)
• Boiling Point: 472.2°Cat760mmHg
• Flash Point: 175.7°C
• PSA: 20.23000
• Density: 1.241g/cm³
• LogP: 4.28100

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 16,17-Dihydro-11-methyl-15H-cyclopenta[a]phenanthren-17-ol

There total 1 articles about 16,17-Dihydro-11-methyl-15H-cyclopenta[a]phenanthren-17-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

11-methyl-16,17-dihydro-15H-cyclopenta-phenanthren-17-one (892-17-1) → 11-Methyl-16,17-dihydro-15H-cyclopenta[a]phenanthren-17-ol (40951-13-1)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; water;

DOI:10.1039/P19730001255

Reference yield:

11-Methyl-16,17-dihydro-15H-cyclopenta[a]phenanthren-17-ol (40951-13-1) → (16R,17S)-11-Methyl-16,17-dihydro-15H-cyclopenta[a]phenanthrene-16,17-diol (42123-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) TsCl, Py, (ii) (heating), collidine

2: (i) OsO₄, Py, (ii) Na₂S₂O₅, aq. Py

DOI:10.1039/P19730001255

upstream raw materials:

11-methyl-16,17-dihydro-15H-cyclopenta-phenanthren-17-one

Downstream raw materials:

(16R,17S)-11-Methyl-16,17-dihydro-15H-cyclopenta[a]phenanthrene-16,17-diol

Refernces