4-Amino-3,5,6-trichloropyridine-2-carbonitrile

Base Information

• Chemical Name: 4-Amino-3,5,6-trichloropyridine-2-carbonitrile
• CAS No.: 14143-60-3
• Molecular Formula: C6H2 Cl3 N3
• Molecular Weight: 222.461
• Hs Code.: 2933399090
• European Community (EC) Number: 237-992-1
• UNII: 6PFC8ZKY2D
• DSSTox Substance ID: DTXSID6027763
• Nikkaji Number: J216.881B
• Wikidata: Q81983965
• Mol file: 14143-60-3.mol

Synonyms:4-Amino-3,5,6-trichloropicolinonitrile;14143-60-3;4-Amino-3,5,6-trichloropyridine-2-carbonitrile;4-Amino-3,5,6-trichloro-2-pyridinecarbonitrile;6PFC8ZKY2D;2-Pyridinecarbonitrile, 4-amino-3,5,6-trichloro-;Picolinonitrile, 4-amino-3,5,6-trichloro-;EINECS 237-992-1;MFCD00185831;C6H2Cl3N3;UNII-6PFC8ZKY2D;DTXSID6027763;SCHEMBL21860793;STL326540;AKOS002348822;CS-0334186;4-AMINO-3,5,6-TRICHLORO-2-CYANOPYRIDINE;F3097-0568

Chemical Property of 4-Amino-3,5,6-trichloropyridine-2-carbonitrile

Chemical Property:

• Vapor Pressure: 9.19E-06mmHg at 25°C
• Boiling Point: 373.1°Cat760mmHg
• Flash Point: 179.4°C
• PSA: 62.70000
• Density: 1.71g/cm³
• LogP: 3.07688
• Storage Temp.: 2-8°C
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 220.931430
• Heavy Atom Count: 12
• Complexity: 213

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-3,5,6-trichloropicolinonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(#N)C1=C(C(=C(C(=N1)Cl)Cl)N)Cl

Technology Process of 4-Amino-3,5,6-trichloropyridine-2-carbonitrile

There total 3 articles about 4-Amino-3,5,6-trichloropyridine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.2%

3,4,5,6-tetrachloropicolinonitrile (17824-83-8) → 4-amino-3,5,6-trichloro-pyridine-2-carbonitrile (14143-60-3) + 4,6-diamino-3,5-dichloro-2-cyanopyridine

Guidance literature:

With potassium cyanate; In water; N,N-dimethyl-formamide; at 125 ℃; for 0.5h;

Reference yield: 81.3%

3,4,5,6-tetrachloropicolinonitrile (17824-83-8) → 4-amino-3,5,6-trichloro-pyridine-2-carbonitrile (14143-60-3) + 6-amino-3,4,5-trichloro-2-cyanopyridine

Guidance literature:

With ammonia; In dimethyl sulfoxide; at 50 ℃;

Reference yield: 55.4%

3,4,5,6-tetrachloropicolinonitrile (17824-83-8) → 4-amino-3,5,6-trichloro-pyridine-2-carbonitrile (14143-60-3) + 4,6-diamino-3,5-dichloro-2-cyanopyridine + 6-amino-3,4,5-trichloro-2-cyanopyridine

Guidance literature:

With ammonia; at 100 ℃; for 10h;

upstream raw materials:

3,4,5,6-tetrachloropicolinonitrile