Antienite

Base Information

Chemical Name:Antienite
CAS No.:5719-88-0
Molecular Formula:C₉H₈N₂S₂
Molecular Weight:208.308
Hs Code.:
UNII:50Z1JVP72H
DSSTox Substance ID:DTXSID90964561
Nikkaji Number:J2.376.438E
Wikidata:Q27260837
NCI Thesaurus Code:C74151
ChEMBL ID:CHEMBL1789329

Synonyms:Antienite;Antienite [INN];5029-05-0;Antienitum;Antienito;R 8025;UNII-50Z1JVP72H;50Z1JVP72H;5719-88-0;6-thiophen-2-yl-5,6-dihydroimidazo[2,1-b][1,3]thiazole;R 8141;R-8025;R-8141;C9H8N2S2;(+-)-5,6-Dihydro-6-(2-thienyl))imidazo(2,1-b)thiazole;(+-)-5,6-Dihydro-6-(2-thienyl)imidazo(2,1-b)thiazole;C9-H8-N2-S2;Imidazo(2,1-b)thiazole, 5,6-dihydro-6-(2-thienyl)-, (+-)-;THIAZOTHIELITE;SCHEMBL2734584;CHEMBL1789329;DTXSID90964561;AKOS033980134;Q27260837;Imidazo[2,1-b]thiazole, 5,6-dihydro-6-(2-thienyl)-;Z1269189514;( -)-5,6-Dihydro-6-(2-thienyl))imidazo(2,1-b)thiazole;6-(Thiophen-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole;(+/-)-5,6-DIHYDRO-6-(2-THIENYL)IMIDAZO(2,1-B)THIAZOLE;Imidazo[2,1-b]thiazole, 5,6-dihydro-6-(2-thienyl)-, (.+.)-

Suppliers and Price of Antienite

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Antienite

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:208.01289061
Heavy Atom Count:13
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(N=C2N1C=CS2)C3=CC=CS3

Technology Process of Antienite

There total 4 articles about Antienite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 6691-91-4
2-(2-imino-thiazol-3-yl)-1-thiophen-2-yl-ethanol

: 5719-88-0,5029-05-0
Antienit, 5,6-Dihydro-6-(2-thienyl)-imidazo<2,1-b>thiazol

Guidance literature:: With thionyl chloride; In dichloromethane; at 4 ℃; for 2.5h; Inert atmosphere; Reflux;
DOI:10.1016/j.bmcl.2011.02.089

Reference yield:

: 5068-68-8
2-(2-imino-thiazol-3-yl)-1-thiophen-2-yl-ethanone

: 5719-88-0,5029-05-0
Antienit, 5,6-Dihydro-6-(2-thienyl)-imidazo<2,1-b>thiazol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 10 - 20 °C / Inert atmosphere

2: thionyl chloride / dichloromethane / 2.5 h / 4 °C / Inert atmosphere; Reflux

With sodium tetrahydroborate; thionyl chloride; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2011.02.089