1-(3-Fluorophenyl)piperazine

Base Information

Chemical Name:1-(3-Fluorophenyl)piperazine
CAS No.:3801-89-6
Molecular Formula:C10H13FN2
Molecular Weight:180.225
Hs Code.:2933599090
European Community (EC) Number:223-271-9
UNII:B46UBR8BEE
DSSTox Substance ID:DTXSID40191426
Nikkaji Number:J217.688B
Wikidata:Q72476300
ChEMBL ID:CHEMBL269784
Mol file:3801-89-6.mol

Synonyms:1-(3-Fluorophenyl)piperazine;3801-89-6;Piperazine, 1-(3-fluorophenyl)-;1-(3-fluorophenyl)-piperazine;1-(3-Fluoro-phenyl)-piperazine;EINECS 223-271-9;B46UBR8BEE;N-(3-Fluorophenyl)piperazine;CHEMBL269784;MFCD03412122;Piperazine,1-(3-fluorophenyl)-;3-fluorophenyl piperazine;UNII-B46UBR8BEE;D07LSC;4-(3-fluorophenyl)piperazine;SCHEMBL315894;DTXSID40191426;1-(M-FLUOROPHENYL)PIPERAZINE;BDBM50017455;AKOS000101159;FS-1513;PIPERAZINE, 1-(M-FLUOROPHENYL)-;1-(3-fluorophenyl)piperazine, AldrichCPR;AS-10296;BL007993;A6453;CS-0106248;FT-0647975;2-Methyl-N-(3-trifluoromethylphenyl)propanamide

Suppliers and Price of 1-(3-Fluorophenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Fluorophenyl)-piperazine
1g
$ 185.00

SynQuest Laboratories
1-(3-Fluorophenyl)piperazine 97%
25 g
$ 465.00

SynQuest Laboratories
1-(3-Fluorophenyl)piperazine 97%
1 g
$ 60.00

SynQuest Laboratories
1-(3-Fluorophenyl)piperazine 97%
250 mg
$ 30.00

SynQuest Laboratories
1-(3-Fluorophenyl)piperazine 97%
5 g
$ 175.00

CHESS?
1-(3-Fluorophenyl)-piperazine >98
2 g
$ 10920.00

CHESS?
1-(3-Fluorophenyl)-piperazine >98
1 g
$ 6830.00

American Custom Chemicals Corporation
1-(3-FLUOROPHENYL)PIPERAZINE 95.00%
5G
$ 1206.98

American Custom Chemicals Corporation
1-(3-FLUOROPHENYL)PIPERAZINE 95.00%
1G
$ 721.88

AK Scientific
1-(3-Fluorophenyl)piperazine
1g
$ 98.60

Total 33 raw suppliers

Chemical Property of 1-(3-Fluorophenyl)piperazine

Chemical Property:

Appearance/Colour:liqui
Boiling Point:301.664 °C at 760 mmHg
PKA:8.85±0.10(Predicted)
Flash Point:136.242 °C
PSA：15.27000
Density:1.113 g/cm³
LogP:1.62910
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:180.10627659
Heavy Atom Count:13
Complexity:157

Purity/Quality:

99%, ^*data from raw suppliers

1-(3-Fluorophenyl)-piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 20/21/22-36/37/38-52-22
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=CC(=CC=C2)F
Uses 1-(3-Fluorophenyl)-piperazine is a Piperazine (P480100) derivative. Piperazine Dihydrochloride is an anthelmintic agent used in the treatment of parasitic worms in animals.

Technology Process of 1-(3-Fluorophenyl)piperazine

There total 7 articles about 1-(3-Fluorophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 3801-89-6
1-(3-fluorophenyl)piperazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 78.0%

: 1073-06-9
3-fluorobromobenzene

: 3801-89-6
1-(3-fluorophenyl)piperazine

Guidance literature:: With piperazine; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; Heating / reflux;

Reference yield: 51.9%

: 110-85-0
piperazine

: 625-98-9
3-chlorofluorobenzene

: 3801-89-6
1-(3-fluorophenyl)piperazine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate; ruphos; In 1,4-dioxane; at 100 ℃; for 1h;
DOI:10.3390/molecules26113182