2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid

Base Information

• Chemical Name: 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid
• CAS No.: 61019-32-7
• Molecular Formula: C7H7N3OS2
• Molecular Weight: 251.374
• Mol file: 61019-32-7.mol

Synonyms:

Chemical Property of 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.413g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid

There total 6 articles about 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

carbon disulfide (75-15-0,12122-00-8) + isoniazid (54-85-3,7640-37-1) → potassium 4-pyridinyldithiocarbazate (61019-32-7)

Guidance literature:

With potassium hydroxide; In ethanol;

DOI:10.1007/s00044-013-0507-6

Reference yield:

pyridine-4-carboxylic acid (55-22-1) → potassium 4-pyridinyldithiocarbazate (61019-32-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / conc. H₂SO₄ / methanol / 25 h / Heating

2: KOH / ethanol / 2 h

With potassium hydroxide; hydrazine hydrate; sulfuric acid; In methanol; ethanol;

DOI:10.1211/0022357011775307

Reference yield:

isoniazid (54-85-3,7640-37-1) → potassium 4-pyridinyldithiocarbazate (61019-32-7)

Guidance literature:

With carbon disulfide; potassium hydroxide;

DOI:10.1021/ja01598a077

upstream raw materials:

isoniazid

carbon disulfide

pyridine-4-carboxylic acid

4-pyridinecarboxylic acid, methyl ester

Downstream raw materials:

5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-thione

4-amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol

5-(pyridin-4'-yl)-1,3,4-thiadiazole-2(3H)-thione

C₁₃H₁₁N₅S

Refernces

• 1、 Bharty,Dani,Nath,Bharti,Singh,Prakash, Om,Singh, Ranjan K.,Butcher. "Syntheses, structural and thermal studies on Zn(II) complexes of 5-aryl-1,3,4-oxadiazole-2-thione and dithiocarbamates: Antibacterial activity and DFT calculations". . p. 84 - 95. Retrieved 2015.
• 2、 Bharty, M. K.,Butcher, R. J.,Chandra, S.,Gond, M. K.,Jaiswal, S.,Kushwaha, D.,Maiti, B.. "Synthesis, structural characterization, DFT, fluorescence, and redox behaviour of 4-[5-(2-picolylsulfanyl)-1,3,4-oxadiazole-2-yl]-pyridine". . . Retrieved 2021/10/19.
• 3、 Pathak, Prateek,Novak, Jurica,Shukla, Parjanya K.,Grishina, Maria,Potemkin, Vladimir,Verma, Amita. "Design, synthesis, antibacterial evaluation, and computational studies of hybrid oxothiazolidin–1,2,4-triazole scaffolds". . . Retrieved 2021/03/08.