[2-methoxy-4-[(Z)-[[2-(4-methylphenoxy)acetyl]hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate

Base Information

• Chemical Name: [2-methoxy-4-[(Z)-[[2-(4-methylphenoxy)acetyl]hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate
• CAS No.: 5523-87-5
• Molecular Formula: C22H20N2O5S
• Molecular Weight: 424.4696
• DSSTox Substance ID: DTXSID60416461
• Mol file: 5523-87-5.mol

Synonyms:5523-87-5;[2-methoxy-4-[(Z)-[[2-(4-methylphenoxy)acetyl]hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate;AC1NSHI2;DTXSID60416461

Chemical Property of [2-methoxy-4-[(Z)-[[2-(4-methylphenoxy)acetyl]hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.25g/cm³
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 9
• Exact Mass: 424.10929292
• Heavy Atom Count: 30
• Complexity: 594

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)OCC(=O)NN=CC2=CC(=C(C=C2)OC(=O)C3=CC=CS3)OC
• Isomeric SMILES: CC1=CC=C(C=C1)OCC(=O)N/N=C\C2=CC(=C(C=C2)OC(=O)C3=CC=CS3)OC

Technology Process of [2-methoxy-4-[(Z)-[[2-(4-methylphenoxy)acetyl]hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate

There total 5 articles about [2-methoxy-4-[(Z)-[[2-(4-methylphenoxy)acetyl]hydrazinylidene]methyl]phenyl] thiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-?-Cyano-tricyclin → Iso-α-santalol (5523-87-5,63569-00-6,88197-55-1)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. KOH / ethane-1,2-diol / 75 h / Heating

2: LiAlH₄

3: SOCl₂, Py

4: (i) Mg, Et₂O, (ii) /BRN= 1209258/

With pyridine; potassium hydroxide; lithium aluminium tetrahydride; thionyl chloride; In ethylene glycol;

Reference yield:

(-)-?-Brom-tricyclin → Iso-α-santalol (5523-87-5,63569-00-6,88197-55-1)

Guidance literature:

Multi-step reaction with 5 steps

2: aq. KOH / ethane-1,2-diol / 75 h / Heating

3: LiAlH₄

4: SOCl₂, Py

5: (i) Mg, Et₂O, (ii) /BRN= 1209258/

With pyridine; potassium hydroxide; lithium aluminium tetrahydride; thionyl chloride; In ethylene glycol;

Reference yield:

(-)-Tricyclonorekasantalsaeure (59300-52-6) → Iso-α-santalol (5523-87-5,63569-00-6,88197-55-1)

Guidance literature:

Multi-step reaction with 3 steps

1: LiAlH₄

2: SOCl₂, Py

3: (i) Mg, Et₂O, (ii) /BRN= 1209258/

With pyridine; lithium aluminium tetrahydride; thionyl chloride;

upstream raw materials:

2-methylpropenal

(-)-Tricyclonorekasantalsaeure