misonidazole-guanosine product

Base Information

• Chemical Name: misonidazole-guanosine product
• CAS No.: 13351-91-2
• Molecular Formula: C₁₂H₁₅N₅O₇
• Molecular Weight: 341.28
• Mol file: 13351-91-2.mol

Synonyms:N,1-Glyoxalguanosine

Chemical Property of misonidazole-guanosine product

Chemical Property:

• Vapor Pressure: 5.47E-29mmHg at 25°C
• Boiling Point: 827.2°Cat760mmHg
• PKA: 10.68±0.40(Predicted)
• Flash Point: 454.1°C
• PSA: 175.12000
• Density: 2.47g/cm³
• LogP: -3.42270

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of misonidazole-guanosine product

There total 2 articles about misonidazole-guanosine product which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Glyoxal (131543-46-9,107-22-2) + G (118-00-3) → (6R,7R)-3-(β-D-erythro-pentafuranosyl)-5,6,7-trihydro-6,7-dihydroxy-imidazo[1,2-a]purine-9-one (13351-91-2) + (6S,7S)-3-(β-D-erythro-pentafuranosyl)-5,6,7-trihydro-6,7-dihydroxy-imidazo[1,2-a]purine-9-one (1318765-03-5)

Guidance literature:

In water; at 37 ℃; for 2h; pH=7.4; aq. phosphate buffer;

DOI:10.1002/chir.20875

Reference yield:

(6S,7S)-3-(β-D-erythro-pentafuranosyl)-5,6,7-trihydro-6,7-dihydroxy-imidazo[1,2-a]purine-9-one (1318765-03-5) → (6R,7R)-3-(β-D-erythro-pentafuranosyl)-5,6,7-trihydro-6,7-dihydroxy-imidazo[1,2-a]purine-9-one (13351-91-2)

Guidance literature:

at 37 ℃; for 45h; Kinetics; Mechanism; Neutral aq. solution;

DOI:10.1002/chir.20875

upstream raw materials:

(6S,7S)-3-(β-D-erythro-pentafuranosyl)-5,6,7-trihydro-6,7-dihydroxy-imidazo[1,2-a]purine-9-one

Glyoxal

G

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