oxopropaline D

Base Information

Chemical Name:oxopropaline D
CAS No.:152752-59-5
Molecular Formula:C₁₅H₁₄N₂O₃
Molecular Weight:270.288
Hs Code.:
Mol file:152752-59-5.mol

Synonyms:9H-Pyrido[3,4-b]indole,1-propanone deriv.; (+)-Oxopropaline D; G 324D; Oxopropaline D

Suppliers and Price of oxopropaline D

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of oxopropaline D

Chemical Property:

Vapor Pressure:1.3E-15mmHg at 25°C
Boiling Point:607.5°Cat760mmHg
Flash Point:321.2°C
PSA：86.21000
Density:1.43g/cm³
LogP:1.56040

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of oxopropaline D

There total 26 articles about oxopropaline D which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 261353-90-6
1-(2,3-O-isopropylidenepropionyl)-4-methyl-9H-pyrido[3,4-b]indole

: 152752-59-5
(-)-oxopropaline D

Guidance literature:: With methanol; sulfuric acid; at 20 ℃; for 1h;
DOI:10.1248/cpb.48.108

Reference yield: 63.0%

: 261353-86-0
1-(2,3-O-isopropylidenepropionyl)-4-methyl-9H-pyrido[3,4-b]indole

: 152752-59-5
(+)-oxopropaline D

Guidance literature:: With methanol; sulfuric acid; at 20 ℃; for 1h;
DOI:10.1248/cpb.48.108

Reference yield:

: 206557-32-6
9-(methoxymethyl)-4-methyl-9H-pyrido[3,4-b]indole

: 152752-59-5
(-)-oxopropaline D

Guidance literature:: Multi-step reaction with 12 steps

1: mCPBA / CH₂Cl₂ / 5 h / 20 °C

2: Ac₂O / 3 h / 110 °C

3: 80 percent / pyridine / CH₂Cl₂ / 3 h / 0 °C

4: 86 percent / Et₃N; Pd(OAc)2; 1,1'-bis(diphenylphosphino)ferrocene / dimethylformamide / 3 h / 80 °C

5: 94 percent / CF₃SO₃H; trimethyl orthoformate; methanol / nitromethane / 1 h / 100 °C

6: 98 percent / diisobutylaluminunm hydride / hexane; CH₂Cl₂ / 1 h / -78 °C

7: 91 percent / tetrahydrofuran / 0.5 h / 0 °C

8: 98 percent / imidazole / dimethylformamide / 1 h / 60 °C

9: 64 percent / AD-mix-α / 2-methyl-propan-2-ol; H2O / 24 h / 0 °C

10: 45 percent / p-TsOH / 24 h / 65 °C

11: 80 percent / MnO₂ / CH₂Cl₂ / 8 h / 20 °C

12: 86 percent / 0.8 percent H₂SO₄; MeOH / 1 h / 20 °C

With pyridine; 1H-imidazole; methanol; manganese(IV) oxide; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; AD-mix-α; trifluorormethanesulfonic acid; sulfuric acid; acetic anhydride; diisobutylaluminium hydride; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; trimethyl orthoformate; In tetrahydrofuran; nitromethane; hexane; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1: Oxidation / 2: Rearrangement / 3: Esterification / 4: cross-coupling reaction / 5: dealkylation / 6: Reduction / 7: Grignard reaction / 8: silylation / 9: assymetric dihydroxylation / 10: acetonization; desilylation / 11: Oxidation / 12: Hydrolysis;
DOI:10.1248/cpb.48.108