trans-Dihydronarciclasine

Base Information

Chemical Name:trans-Dihydronarciclasine
CAS No.:40042-05-5
Molecular Formula:C₁₄H₁₅NO₇
Molecular Weight:309.276
Hs Code.:
Nikkaji Number:J2.448.457B
Wikidata:Q105249705
Metabolomics Workbench ID:136555
ChEMBL ID:CHEMBL464432
Mol file:40042-05-5.mol

Synonyms:dihydronarciclasine;dihydronarciclasine, (2S-(2alpha,3beta,4beta,4abeta,11bbeta))-isomer;trans-dihydronarciclasine

Suppliers and Price of trans-Dihydronarciclasine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of trans-Dihydronarciclasine

Chemical Property:

Vapor Pressure:5E-17mmHg at 25°C
Boiling Point:635.6°C at 760 mmHg
Flash Point:338.2°C
Density:1.705g/cm³
XLogP3:-0.6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:309.08485182
Heavy Atom Count:22
Complexity:474

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2C(C(C(C1O)O)O)NC(=O)C3=C(C4=C(C=C23)OCO4)O
Isomeric SMILES:C1[C@H]2[C@H]([C@@H]([C@@H]([C@H]1O)O)O)NC(=O)C3=C(C4=C(C=C23)OCO4)O

Technology Process of trans-Dihydronarciclasine

There total 2 articles about trans-Dihydronarciclasine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 29477-83-6,220751-83-7
narciclasine

: 40041-93-8
iso-narciclasine

: 40042-04-4
cis-dihydronarciclasine

: 34200-34-5,40042-04-4,40042-05-5
(2S,3R,4S,4aR,11bR)-2,3,4,7-tetrahydroxy-1,3,4,4a,5,11b-hexahydro-[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one

Guidance literature:: With platinum(IV) oxide; hydrogen; In ethanol;
DOI:10.1021/np9001948

Reference yield:

: 29477-83-6,220751-83-7
narciclasine

: 34200-34-5,40042-04-4,40042-05-5
(2S,3R,4S,4aR,11bR)-2,3,4,7-tetrahydroxy-1,3,4,4a,5,11b-hexahydro-[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: (i) H₂, CaCO₃, Pd, EtOH, (ii) /BRN= 385737/, Py

2: Ba(OH)2 / ethanol

With barium dihydroxide; In ethanol;