ACONOSINE

Base Information

• Chemical Name: ACONOSINE
• CAS No.: 38839-95-1
• Molecular Formula: C₂₂H₃₅NO₄
• Molecular Weight: 377.524
• Mol file: 38839-95-1.mol

Synonyms:Acnosine;Aconosine

Chemical Property of ACONOSINE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 512.9°Cat760mmHg
• Flash Point: 264°C
• PSA: 62.16000
• Density: 1.26g/cm³
• LogP: 1.45250

Purity/Quality:

> 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACONOSINE

There total 5 articles about ACONOSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

oxoaconosine (87077-09-6) → aconosine (38839-95-1)

Guidance literature:

With lithium aluminium tetrahydride; In 1,4-dioxane; for 2h; Heating;

Reference yield:

cammaconine (32152-70-8,11037-01-7,58969-47-4) → aconosine (38839-95-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 62 mg / potassium permanganate / acetone; H₂O / 15 °C

2: manganese dioxide, potassium permanganate / acetone; H₂O; acetic acid / 23 h / 50 °C

3: 155 mg / 0.17 h / 220 - 230 °C / 15 Torr

4: 84 percent / sodium borohydride / methanol / 0.33 h

5: 71 percent / lithium alumunium hydride / dioxane / 2 h / Heating

With manganese(IV) oxide; sodium tetrahydroborate; potassium permanganate; lithium aluminium tetrahydride; In 1,4-dioxane; methanol; water; acetic acid; acetone;

Reference yield:

oxocammaconine (87077-10-9) → aconosine (38839-95-1)

Guidance literature:

Multi-step reaction with 4 steps

1: manganese dioxide, potassium permanganate / acetone; H₂O; acetic acid / 23 h / 50 °C

2: 155 mg / 0.17 h / 220 - 230 °C / 15 Torr

3: 84 percent / sodium borohydride / methanol / 0.33 h

4: 71 percent / lithium alumunium hydride / dioxane / 2 h / Heating

With manganese(IV) oxide; sodium tetrahydroborate; potassium permanganate; lithium aluminium tetrahydride; In 1,4-dioxane; methanol; water; acetic acid; acetone;

upstream raw materials:

oxoaconosine

cammaconine

14-dehydrooxoaconosine

14-dehydrooxocammaconic acid