11-Hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate

Base Information

• Chemical Name: 11-Hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate
• CAS No.: 20424-00-4
• Molecular Formula: C24H32 O5
• Molecular Weight: 400.515
• DSSTox Substance ID: DTXSID70942600
• Mol file: 20424-00-4.mol

Synonyms:11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate;DTXSID70942600;LS-118495

Chemical Property of 11-Hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate

Chemical Property:

• Vapor Pressure: 6.07E-14mmHg at 25°C
• Melting Point: 227-229 °C
• Boiling Point: 540.6 °C at 760 mmHg
• PKA: 14.09±0.70(Predicted)
• Flash Point: 180.9 °C
• PSA: 80.67000
• Density: 1.2 g/cm³
• LogP: 3.54610
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 400.22497412
• Heavy Atom Count: 29
• Complexity: 825

Purity/Quality:

98%Min ^*data from raw suppliers

21-Deoxyprednisolone17α-Propionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)C(=O)C
• Description: Deprodone propionate is a new topical antiinflammatory corticosteroid. In animal studies, it exhibited an extremely low skin irritation rate. Another potential use is as an antiasthmatic agent.
• Uses: Ester of 21-Deoxyprednisolone 17α-Propionate is a topical antiinflammatory agent.

Technology Process of 11-Hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate

There total 1 articles about 11-Hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 11β,17-dihydroxypregna-1,4-diene-3,20-dione 17-propionate (20424-00-4)

Guidance literature:

21-Desoxyprednisolon-17α-propionat-11β-nitrat, Zn, AcOH;

Refernces