2-(1-Phenylethyl)naphthalene-1-carboxylic acid

Base Information

Chemical Name:2-(1-Phenylethyl)naphthalene-1-carboxylic acid
CAS No.:81194-85-6
Molecular Formula:C19H16O2
Molecular Weight:276.335
Hs Code.:
NSC Number:171722
DSSTox Substance ID:DTXSID80305823

Synonyms:81194-85-6;2-(1-phenylethyl)naphthalene-1-carboxylic acid;NSC171722;DTXSID80305823;NSC-171722

Suppliers and Price of 2-(1-Phenylethyl)naphthalene-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(1-Phenylethyl)naphthalene-1-carboxylic acid

Chemical Property:

Vapor Pressure:2.48E-09mmHg at 25°C
Boiling Point:462°Cat760mmHg
Flash Point:211.2°C
Density:1.187g/cm³
XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:276.115029749
Heavy Atom Count:21
Complexity:359

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3C=C2)C(=O)O

Technology Process of 2-(1-Phenylethyl)naphthalene-1-carboxylic acid

There total 4 articles about 2-(1-Phenylethyl)naphthalene-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 81194-76-5
3-methyl-3-phenyl-3H-naphtho[1,2-c]furan-1-one

: 81194-85-6
2-(1-phenyl-ethyl)-[1]naphthoic acid

Guidance literature:: With pyridine; potassium hydroxide; zinc; Heating; overnight;
DOI:10.1021/jo00132a026

Reference yield:

: 81194-85-6
2-(1-phenyl-ethyl)-[1]naphthoic acid

Guidance literature:: With hydrogenchloride; amalgamated zinc; acetic acid;
DOI:10.1021/ja01303a006

Reference yield:

: 879-18-5
naphthalene-1-carbonic acid chloride

: 81194-85-6
2-(1-phenyl-ethyl)-[1]naphthoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 18.5 g / diethyl ether / 1 h / 0 °C

2: 1.) TMEDA, triphenylmethyl chloride, sec-BuLi / 1.) ether, cyclohexane, -78 deg C, 1 h, 2.) a) -78 deg C, 1 h, b) room temp., 3 h

3: 93 percent / Zn, pyridine, 10percent KOH / Heating; overnight

With pyridine; potassium hydroxide; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; trityl chloride; zinc; In diethyl ether;
DOI:10.1021/jo00132a026