Chemical Property of Pentosidine
Chemical Property:
- Vapor Pressure:7.05E-19mmHg at 25°C
- Boiling Point:655.6°Cat760mmHg
- PKA:2.50±0.24(Predicted)
- Flash Point:350.3°C
- PSA：169.38000
- Density:1.47g/cm3
- LogP:2.09110
- XLogP3:-4.7
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:9
- Rotatable Bond Count:12
- Exact Mass:378.20155333
- Heavy Atom Count:27
- Complexity:494
- Purity/Quality:
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98%Min *data from raw suppliers
Pentosidine *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1=CN(C2=NC(=NC2=C1)NCCCC(C(=O)O)N)CCCCC(C(=O)O)N
- Isomeric SMILES:C1=CN(C2=NC(=NC2=C1)NCCC[C@@H](C(=O)O)N)CCCC[C@@H](C(=O)O)N
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Description
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling. Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of this AGE is catabolized before excretion.
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Uses
A biochemical marker of bone turnover for management of metabolic bone diseases.
