1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride

Base Information

Chemical Name:1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride
CAS No.:110629-25-9
Molecular Formula:C26H31 N5 O2 . 3 Cl H
Molecular Weight:554.9395
Hs Code.:
DSSTox Substance ID:DTXSID00149342

Synonyms:1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride;2,6-Dimethyl-3-nitro-4-((2-(4-diphenylmethyl-1-piperazinyl)ethyl)amino)pyridine 3HCl;110629-25-9;C26H31N5O2.3ClH;DTXSID00149342;VYAGFSLMTCXVGS-UHFFFAOYSA-N;C26-H31-N5-O2.3Cl-H;LS-112004;2,6-dimethyl-3-nitro-4-[(2-{4-diphenylmethyl-1-piperazinyl}ethyl)amino]pyridine trihydrochloride

Suppliers and Price of 1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride

Chemical Property:

Vapor Pressure:1.98E-14mmHg at 25°C
Boiling Point:601.6°Cat760mmHg
Flash Point:317.6°C
Density:g/cm³
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:553.177808
Heavy Atom Count:36
Complexity:576

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=N1)C)[N+](=O)[O-])NCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl.Cl

Technology Process of 1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride

There total 4 articles about 1-Piperazineethanamine, N-(2,6-dimethyl-3-nitro-4-pyridinyl)-4-(diphenylmethyl)-, trihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 841-77-0
diphenylmethylpiperazine

: 110629-58-8
4-<(2-chloroethyl)amino>-2,6-dimethyl-3-nitropyridine

: 110629-25-9
2,6-dimethyl-3-nitro-4<(2-(4-diphenylmethyl-1-piperiazinyl)-ethyl)amino>pyridine trihydrochloride

Guidance literature:: With hydrogenchloride; triethylamine; In N,N-dimethyl-formamide; for 2h; Heating;
DOI:10.1016/0223-5234(89)90003-2

Reference yield:

: 79387-51-2
1-diphenylmethyl-4-(2-chloroethyl)piperazine

: 18232-98-9
2,6-dimethyl-3-nitro-pyridin-4-ylamine

: 110629-25-9
2,6-dimethyl-3-nitro-4<(2-(4-diphenylmethyl-1-piperiazinyl)-ethyl)amino>pyridine trihydrochloride

Guidance literature:: With triethylamine; In ethanol; ethyl acetate; isopropyl alcohol;

Reference yield:

: 15513-48-1
4-chloro-2,6-dimethyl-3-nitropyridine

: 110629-25-9
2,6-dimethyl-3-nitro-4<(2-(4-diphenylmethyl-1-piperiazinyl)-ethyl)amino>pyridine trihydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / triethylamine / propan-2-ol / 20 h / Heating

2: 98 percent / thionylchloride / CH₂Cl₂ / 2 h / Heating

3: 62 percent / 1.) triethylamine; 2.) ethanolic HCl / dimethylformamide / 2 h / Heating

With hydrogenchloride; thionyl chloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1016/0223-5234(89)90003-2