1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)-

Base Information

Chemical Name:1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)-
CAS No.:126567-80-4
Molecular Formula:C₁₆H₂₁ClN₄O
Molecular Weight:320.822
Hs Code.:
DSSTox Substance ID:DTXSID60155227
Wikidata:Q83023051

Synonyms:1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)-;4-Chloro-N,N-diethyl-2-((1-methylethyl)amino)-1,8-naphthyridine-3-carboxamide;126567-80-4;DTXSID60155227;LS-95881

Suppliers and Price of 1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)-

Chemical Property:

Vapor Pressure:2.82E-10mmHg at 25°C
Boiling Point:503.8°C at 760 mmHg
Flash Point:258.5°C
Density:1.219g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:320.1403890
Heavy Atom Count:22
Complexity:375

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=C(N=C2C(=C1Cl)C=CC=N2)NC(C)C

Technology Process of 1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)-

There total 4 articles about 1,8-Naphthyridine-3-carboxamide, 4-chloro-N,N-diethyl-2-((1-methylethyl)amino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.3%

: 75-31-0
isopropylamine

: 126567-71-3
2,4-dichloro-N,N-diethyl-1,8-naphthyridine-3-carboxamide

: 126567-80-4
4-Chloro-2-isopropylamino-[1,8]naphthyridine-3-carboxylic acid diethylamide

: 126567-83-7
2-Chloro-4-isopropylamino-[1,8]naphthyridine-3-carboxylic acid diethylamide

Guidance literature:: In ethanol; for 24h; Ambient temperature;

Reference yield:

: 5345-47-1
2-aminopyridin-3-carboxylic acid

: 126567-80-4
4-Chloro-2-isopropylamino-[1,8]naphthyridine-3-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 33.5 percent / POCl₃ / 4 h / 100 °C

2: 90.5 percent / POCl₃ / 0.5 h / Heating

3: 33.9 percent / ethanol / 24 h / Ambient temperature

With trichlorophosphate; In ethanol;

Reference yield:

: 33567-70-3
ethyl 3-(diethylamino)-3-oxopropanoate

: 126567-80-4
4-Chloro-2-isopropylamino-[1,8]naphthyridine-3-carboxylic acid diethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 33.5 percent / POCl₃ / 4 h / 100 °C

2: 90.5 percent / POCl₃ / 0.5 h / Heating

3: 33.9 percent / ethanol / 24 h / Ambient temperature

With trichlorophosphate; In ethanol;