5-[(2-Chlorophenyl)methyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Base Information

Chemical Name:5-[(2-Chlorophenyl)methyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
CAS No.:83427-51-4
Molecular Formula:C14H14ClNOS
Molecular Weight:279.79
Hs Code.:2934999090
Mol file:83427-51-4.mol

Synonyms:Thieno[3,2-c]pyridin-2(4H)-one,5-[(2-chlorophenyl) methyl]-5,6,7,7a-tetrahydro-;

Suppliers and Price of 5-[(2-Chlorophenyl)methyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-OXO TICLOPIDINE 95.00%
5MG
$ 500.46

Total 4 raw suppliers

Chemical Property of 5-[(2-Chlorophenyl)methyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Chemical Property:

Vapor Pressure:7.27E-08mmHg at 25°C
Melting Point:162-164°C
Refractive Index:1.66
Boiling Point:437.8°Cat760mmHg
Flash Point:218.6°C
PSA：45.61000
Density:1.35g/cm³
LogP:3.05200
Storage Temp.:Hygroscopic, -20?C Freezer, Under Inert Atmosphere

Purity/Quality:

97% ^*data from raw suppliers

2-OXO TICLOPIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Thiolactone metabolite of Ticlopidine (T438325); Ticlopidene metabolite M2.

Technology Process of 5-[(2-Chlorophenyl)methyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

There total 4 articles about 5-[(2-Chlorophenyl)methyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 55142-85-3
ticlopidine

: 688-74-4
boric acid tributyl ester

: 83427-51-4,94188-83-7
5-(2-Chlorobenzyl)-5,6,7,7a-tetrahydro-4H-thieno(3,2-c)-pyridin-2-one

Guidance literature:: With n-butyllithium; dihydrogen peroxide; oxalic acid; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; acetone;

Reference yield: 52.0%

: 83427-51-4,94188-83-7
5-(2-Chlorobenzyl)-5,6,7,7a-tetrahydro-4H-thieno(3,2-c)-pyridin-2-one

: 83427-55-8
5-(2-chlorobenzyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one hydrochloride

Guidance literature:

Reference yield:

: 55142-85-3
ticlopidine

: 83427-51-4,94188-83-7
5-(2-Chlorobenzyl)-5,6,7,7a-tetrahydro-4H-thieno(3,2-c)-pyridin-2-one

Guidance literature:: With glucose-6-phosphate dehydrogenase; α-D-glucose 6-phosphate; cytochrome P₄₅₀ 2C₁₉; NADP; magnesium chloride; In aq. phosphate buffer; at 37 ℃; pH=7.4; Reagent/catalyst; Enzymatic reaction;
DOI:10.1124/dmd.113.053017