Chlorolissoclimide

Base Information

Chemical Name:Chlorolissoclimide
CAS No.:148717-91-3
Molecular Formula:C₂₀H₃₀ClNO₄
Molecular Weight:383.916
Hs Code.:
DSSTox Substance ID:DTXSID80933468
Nikkaji Number:J863.295B
Wikidata:Q82909285
ChEMBL ID:CHEMBL514096
Mol file:148717-91-3.mol

Synonyms:chlorolissoclimide

Suppliers and Price of Chlorolissoclimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Chlorolissoclimide

Chemical Property:

Vapor Pressure:2.97E-15mmHg at 25°C
Boiling Point:567.7°Cat760mmHg
Flash Point:297.2°C
PSA：90.12000
Density:1.24g/cm³
LogP:2.66290
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:383.1863361
Heavy Atom Count:26
Complexity:633

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(CC2(C1CC(C(=C)C2CC(C3CC(=O)NC3=O)O)O)C)Cl)C
Isomeric SMILES:C[C@]12C[C@H](CC([C@@H]1C[C@@H](C(=C)[C@@H]2C[C@@H]([C@H]3CC(=O)NC3=O)O)O)(C)C)Cl

Technology Process of Chlorolissoclimide

There total 10 articles about Chlorolissoclimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: haterumaimide N

: 148717-91-3
chlorolissoclimide

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 4h;
DOI:10.1016/j.bmc.2006.06.043

Reference yield: 55.0%

: C₃₄H₅₀ClNO₇Si

: 148717-91-3
chlorolissoclimide

Guidance literature:: C₃₄H₅₀ClNO₇Si; With ammonia; In methanol; at 23 ℃; for 24h;

With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃;
DOI:10.1021/jacs.5b12308

Reference yield:

: C₁₈H₂₈ClNO₃

: 148717-91-3
chlorolissoclimide

Guidance literature:: Multi-step reaction with 4 steps

1.1: diisobutylaluminium hydride / diethyl ether; toluene / -78 - -25 °C / Inert atmosphere

2.1: 2,4,6-trimethyl-pyridine / dichloromethane / 1 h / -78 °C / Inert atmosphere

3.1: di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / dichloromethane / -78 °C / Inert atmosphere

3.2: 20 h / -78 - -25 °C / Inert atmosphere

4.1: ammonia / methanol / 24 h / 23 °C

4.2: 20 °C

With 2,4,6-trimethyl-pyridine; di-n-butylboryl trifluoromethanesulfonate; ammonia; diisobutylaluminium hydride; N-ethyl-N,N-diisopropylamine; In methanol; diethyl ether; dichloromethane; toluene; 3.1: |Evans Aldol Reaction / 3.2: |Evans Aldol Reaction;
DOI:10.1021/jacs.5b12308