N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Base Information

Chemical Name:N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
CAS No.:4423-58-9
Molecular Formula:C11H14N2O5
Molecular Weight:254.243
Hs Code.:
European Community (EC) Number:225-030-3
NSC Number:63859
Nikkaji Number:J89.938K
Metabolomics Workbench ID:147182
Mol file:4423-58-9.mol

Synonyms:corynecin I;N-acetyl-4-nitrophenylserinol;N-acetyl-4-nitrophenylserinol, (D-threo)-isomer;N-acetyl-4-nitrophenylserinol, (L-threo)-isomer;N-acetyl-p-nitrophenylserinol

Suppliers and Price of N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CorynecinI
5mg
$ 390.00

Cayman Chemical
Corynecin I ≥99%
5mg
$ 469.00

Cayman Chemical
Corynecin I ≥99%
1mg
$ 125.00

Total 6 raw suppliers

Chemical Property of N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Chemical Property:

PSA：115.38000
LogP:1.03930
XLogP3:0
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:254.09027155
Heavy Atom Count:18
Complexity:296

Purity/Quality:

98%min ^*data from raw suppliers

CorynecinI ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(CO)C(C1=CC=C(C=C1)[N+](=O)[O-])O
Isomeric SMILES:CC(=O)N[C@H](CO)[C@@H](C1=CC=C(C=C1)[N+](=O)[O-])O
Description Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.
Uses Corynecin I is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin I is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin I shows a similar species selectivity.

Technology Process of N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

There total 68 articles about N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: