Technology Process of 3,7-Anhydro-1,2-dideoxygluco-oct-2-enitol
There total 8 articles about 3,7-Anhydro-1,2-dideoxygluco-oct-2-enitol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium methylate;
In
methanol;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1039/c3ob41926f
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) Mg / 2) ether, 2 h, reflux
2: 53 percent / pyridine / 24 h / Ambient temperature
3: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 5 h
4: 60 percent / pyridine / 18 h / Ambient temperature
5: 1) sodium benzoate, 2) 0.02 N CH3ONa / 1) DMF, 2 h, reflux, 2) 12 h, room temp.
With
pyridine; sodium benzoate; hydrogen; sodium methylate; magnesium;
palladium on activated charcoal;
In
methanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1) 0.02N NaOCH3, 2) NaH / 1) 3.5 h, 2) DMF, 12 h, r.t.
2: 89 percent / p-TsOH*H2O / CH2Cl2; acetone / 2 h
3: 1) Mg / 2) ether, 2 h, reflux
4: 53 percent / pyridine / 24 h / Ambient temperature
5: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 5 h
6: 60 percent / pyridine / 18 h / Ambient temperature
7: 1) sodium benzoate, 2) 0.02 N CH3ONa / 1) DMF, 2 h, reflux, 2) 12 h, room temp.
With
pyridine; sodium benzoate; hydrogen; sodium methylate; sodium hydride; toluene-4-sulfonic acid; magnesium;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate; acetone;