Technology Process of 3,7-Anhydro-1,2-dideoxygluco-oct-2-enitol
There total 8 articles about 3,7-Anhydro-1,2-dideoxygluco-oct-2-enitol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium methylate;
In
methanol;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1039/c3ob41926f
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) Mg / 2) ether, 2 h, reflux
2: 53 percent / pyridine / 24 h / Ambient temperature
3: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 5 h
4: 60 percent / pyridine / 18 h / Ambient temperature
5: 1) sodium benzoate, 2) 0.02 N CH3ONa / 1) DMF, 2 h, reflux, 2) 12 h, room temp.
With
pyridine; sodium benzoate; hydrogen; sodium methylate; magnesium;
palladium on activated charcoal;
In
methanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1) 0.02N NaOCH3, 2) NaH / 1) 3.5 h, 2) DMF, 12 h, r.t.
2: 89 percent / p-TsOH*H2O / CH2Cl2; acetone / 2 h
3: 1) Mg / 2) ether, 2 h, reflux
4: 53 percent / pyridine / 24 h / Ambient temperature
5: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 5 h
6: 60 percent / pyridine / 18 h / Ambient temperature
7: 1) sodium benzoate, 2) 0.02 N CH3ONa / 1) DMF, 2 h, reflux, 2) 12 h, room temp.
With
pyridine; sodium benzoate; hydrogen; sodium methylate; sodium hydride; toluene-4-sulfonic acid; magnesium;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate; acetone;
