Chemical Property of DELTA12-PROSTAGLANDIN J2
Chemical Property:
- Appearance/Colour:Colorless oil
- Boiling Point:531.2 °C at 760 mmHg
- PKA:4.75±0.10(Predicted)
- Flash Point:289.2 °C
- PSA：74.60000
- Density:1.111 g/cm3
- LogP:4.20040
- Water Solubility.:Soluble in ethanol (>25 mg/ml) and DMSO (>25 mg/ml)
- Purity/Quality:
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99% *data from raw suppliers
delta12-PGJ2(delta12-ProstaglandinJ2) *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 μg/ml. Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand.
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Uses
Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 μg/ml. Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand. delta12-PGJ2 (delta12-Prostaglandin J2) is a decomposition product of PGD2 showing potent antiviral and anti-proliferative activity.
