L-Glyceraldehyde

Base Information

• Chemical Name: L-Glyceraldehyde
• CAS No.: 497-09-6
• Molecular Formula: C3H6 O3
• Molecular Weight: 90.0788
• Hs Code.: 2912491000
• European Community (EC) Number: 207-836-7
• UNII: GI7U82BL5A
• Nikkaji Number: J9.120K
• Wikidata: Q27103431
• Metabolomics Workbench ID: 51539
• Mol file: 497-09-6.mol

Synonyms:Glyceraldehyde,L- (8CI); Propanal, 2,3-dihydroxy-, (S)-; (-)-Glyceraldehyde;(S)-(-)-2,3-Dihydroxypropanal; (S)-Glyceraldehyde; L-(-)-Glyceraldehyde;L-Glyceraldehyde

Chemical Property of L-Glyceraldehyde

Chemical Property:

• Appearance/Colour: yellow viscous liquid.
• Vapor Pressure: 0.0146mmHg at 25°C
• Boiling Point: 126-129 ºC (18 mmHg)，228 °C at 760 mmHg
• PKA: 12.60±0.20(Predicted)
• Flash Point: 106 °C
• PSA: 57.53000
• Density: 1.272 g/cm³
• LogP: -1.46150
• Storage Temp.: 2-8°C
• XLogP3: -1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 90.031694049
• Heavy Atom Count: 6
• Complexity: 43.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-2,3-Dihydroxypropanal(90%inH2O) ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C=O)O)O
• Isomeric SMILES: C([C@@H](C=O)O)O
• Uses: (S)-2,3-Dihydroxypropanal(90% in H2O) is the enantiomer of D-Glyceraldehyde (G598200). Glyceraldehyde is the simplest of all aldoses and is commonly found as an intermediate in carbohydrate metabolism.

Technology Process of L-Glyceraldehyde

There total 25 articles about L-Glyceraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

D-glyceraldehyde 3-phosphate (20283-52-7) → (S)-glyceraldehyde (497-09-6,367-47-5,26793-98-6)

Guidance literature:

With Potato acid phosphatase (Pase); In water; for 4h; pH 3-4 (adjusted with 2 N NaOH);

DOI:10.1021/jo00167a012

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) → (S)-glyceraldehyde (497-09-6,367-47-5,26793-98-6) + L-erythrulose (533-50-6)

Guidance literature:

With triethanolamine; thiamine diphosphate; Escherichia coli formolase; recombinant Escherichia coli D-fructose-6-phosphate aldolase, A₁₂₉S mutant; magnesium sulfate; In water; at 30 ℃; for 48h; pH=7.0; Time; regioselective reaction; Enzymatic reaction;

DOI:10.1021/jacs.1c07872

Reference yield:

C37H46B2O2 → (S)-glyceraldehyde (497-09-6,367-47-5,26793-98-6) + L-erythrulose (533-50-6) + dihydroxyacetone (96-26-4,26776-70-5)

Guidance literature:

With triethanolamine; thiamine diphosphate; Escherichia coli formolase; recombinant Escherichia coli D-fructose-6-phosphate aldolase, A₁₂₉S mutant; magnesium sulfate; In tetrahydrofuran; water; at 30 ℃; for 48h; pH=7.0; Time; enantioselective reaction; Enzymatic reaction;

DOI:10.1021/jacs.1c07872

upstream raw materials:

3,3-dimethoxy-propane-1,2-diol

L-erythronic acid

L-arabinose

L-sorbose

Downstream raw materials:

L-fructose

1-Deoxy-L-threo-pentulose

formic acid

LACTIC ACID

Refernces

• 1、 Bontemps, Sébastien,Clapés, Pere,Desmons, Sarah,Dumon, Claire,Fauré, Régis,Grayson-Steel, Katie,Hurtado, John,Nu?ez-Dallos, Nelson,Vendier, Laure. "Enantioselective Reductive Oligomerization of Carbon Dioxide into l-Erythrulose via a Chemoenzymatic Catalysis". supporting information. p. 16274 - 16283. Retrieved 2021/10/12.
• 2、 Gauss, Dominik,Sánchez-Moreno, Israel,Oroz-Guinea, Isabel,García-Junceda, Eduardo,Wohlgemuth, Roland. "Phosphorylation Catalyzed by Dihydroxyacetone Kinase". supporting information. p. 2892 - 2895. Retrieved 2018/05/15.