3-(Bromo(phenyl)methylene)isoindolin-1-one

Base Information

Chemical Name:3-(Bromo(phenyl)methylene)isoindolin-1-one
CAS No.:5194-49-0
Molecular Formula:C₁₅H₁₀BrNO
Molecular Weight:300.154
Hs Code.:
NSC Number:114986
Mol file:5194-49-0.mol

Synonyms:3-(Bromo(phenyl)methylene)isoindolin-1-one;5194-49-0;NSC114986;NSC-114986

Suppliers and Price of 3-(Bromo(phenyl)methylene)isoindolin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(Bromo(phenyl)methylene)isoindolin-1-one

Chemical Property:

Vapor Pressure:2.27E-09mmHg at 25°C
Boiling Point:479.9°Cat760mmHg
Flash Point:244°C
Density:1.536g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:298.99458
Heavy Atom Count:18
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=C2C3=CC=CC=C3C(=O)N2)Br
Isomeric SMILES:C1=CC=C(C=C1)/C(=C\2/C3=CC=CC=C3C(=O)N2)/Br

Technology Process of 3-(Bromo(phenyl)methylene)isoindolin-1-one

There total 11 articles about 3-(Bromo(phenyl)methylene)isoindolin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: N-methoxy-2-(phenylethynyl)-benzamide

: 40523-47-5,5194-49-0
(Z)-3-{bromo(phenyl)methylene}isoindolin-1-one

Guidance literature:: With ferric(III) bromide; In 1,2-dichloro-ethane; at 80 ℃; for 6h; stereoselective reaction;
DOI:10.1039/d1cc00870f

Reference yield: 86.0%

: 3-{2-(phenylethynyl)phenyl}-1,4,2-dioxazol-5-one

: 40523-47-5,5194-49-0
(Z)-3-{bromo(phenyl)methylene}isoindolin-1-one

Guidance literature:: With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; 15-crown-5; acetic acid; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; sodium bromide; In dichloromethane; 2,2,2-trifluoroethanol; at 40 ℃; for 12h; Sealed tube;
DOI:10.1021/jacs.8b08134

Reference yield: 71.0%

: 80221-08-5
2-(2-phenylethynyl)benzamide

: 40523-47-5,5194-49-0
(Z)-3-{bromo(phenyl)methylene}isoindolin-1-one

Guidance literature:: With bromine; phosphazene base-P₄-tert-butyl; In tetrahydrofuran; hexane; at 25 ℃; for 0.0166667h; Reagent/catalyst; Inert atmosphere;
DOI:10.1021/acs.joc.9b00452