[7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate

Base Information

Chemical Name:[7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate
CAS No.:99396-19-7
Molecular Formula:C₂₇H₃₂N₄O₁₁
Molecular Weight:588.571
Hs Code.:
DSSTox Substance ID:DTXSID50912725
Mol file:99396-19-7.mol

[7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate

Synonyms:7-GPMM;7-N-(4-O-glucopyranosyl)phenyl-9-methoxymitosane

Suppliers and Price of [7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of [7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate

Chemical Property:

Boiling Point:872.1°Cat760mmHg
Flash Point:481.3°C
Density:1.64g/cm³
XLogP3:-1
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:9
Exact Mass:588.20675785
Heavy Atom Count:42
Complexity:1220

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=O)C2=C(C1=O)N3C4C(N4)CC3(C2COC(=O)N)OC)NC5=CC=C(C=C5)OC6C(C(C(C(O6)CO)O)O)O

Technology Process of [7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate

There total 3 articles about [7-Methoxy-12-methyl-10,13-dioxo-11-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanilino]-2,4-diazatetracyclo[7.4.0.02,7.03,5]trideca-1(9),11-dien-8-yl]methyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 134136-38-2
7-N-<4-O-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)phenyl>-9a-methoxymitosane

: 99339-58-9,99396-19-7,99396-20-0,99396-21-1,99396-22-2,99396-25-5,99397-32-7
7-N-<4-O-(β-D-Glucopyranosyl)phenyl>-9a-methoxymitosane

: 134136-39-3
7-N-<4-O-(6-O-Acetyl-β-D-glucopyranosyl)phenyl>-9a-methoxymitosane

Guidance literature:: With methanol; sodium methylate; In methanol; at 20 ℃; for 0.5h;
DOI:10.1248/cpb.39.255

Reference yield:

: 42011-36-9
(2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-(4-aminophenoxy)-tetrahydro-2H-pyran-3,4,5-triyl triacetate

: 99339-58-9,99396-19-7,99396-20-0,99396-21-1,99396-22-2,99396-25-5,99397-32-7
7-N-<4-O-(β-D-Glucopyranosyl)phenyl>-9a-methoxymitosane

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / methanol / 5 h / Heating

2: 75 percent / 28 percent sodium methoxide-methanol / methanol / 0.5 h / 20 °C

With methanol; sodium methylate; In methanol;
DOI:10.1248/cpb.39.255

Reference yield:

: 4055-39-4
mitomycin A

: 99339-58-9,99396-19-7,99396-20-0,99396-21-1,99396-22-2,99396-25-5,99397-32-7
7-N-<4-O-(β-D-Glucopyranosyl)phenyl>-9a-methoxymitosane

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / methanol / 5 h / Heating

2: 75 percent / 28 percent sodium methoxide-methanol / methanol / 0.5 h / 20 °C

With methanol; sodium methylate; In methanol;
DOI:10.1248/cpb.39.255