leukotriene B3

Base Information

Chemical Name:leukotriene B3
CAS No.:88099-35-8
Molecular Formula:C₂₀H₃₄O₄
Molecular Weight:338.488
Hs Code.:
European Community (EC) Number:632-968-0
Nikkaji Number:J337.435A
Mol file:88099-35-8.mol

Synonyms:leukotriene B3;leukotriene B3, (S-(R*,R*-(E,E,Z)))-isomer;LTB3

Suppliers and Price of leukotriene B3

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
LTB3(LeukotrieneB3)
1mg
$ 625.00

Cayman Chemical
Leukotriene B3 ≥97%
100μg
$ 425.00

Cayman Chemical
Leukotriene B3 ≥97%
50μg
$ 224.00

Cayman Chemical
Leukotriene B3 ≥97%
25μg
$ 118.00

Total 3 raw suppliers

Chemical Property of leukotriene B3

Chemical Property:

Vapor Pressure:2.94E-13mmHg at 25°C
Boiling Point:525.9°C at 760 mmHg
Flash Point:285.9°C
PSA：77.76000
Density:1.025g/cm³
LogP:4.38230
XLogP3:4.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:15
Exact Mass:338.24570956
Heavy Atom Count:24
Complexity:385

Purity/Quality:

98%Min ^*data from raw suppliers

LTB3(LeukotrieneB3) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCC(C=CC=CC=CC(CCCC(=O)O)O)O
Isomeric SMILES:CCCCCCCC[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O
Uses LTB3 (Leukotriene B3) is found in leukocytes with proinflammatory properties similar to those of LTA4.

Technology Process of leukotriene B3

There total 19 articles about leukotriene B3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 111037-21-9,130121-31-2,130121-32-3,135570-16-0,135570-17-1,142760-34-7
methyl 5ζ,12ζ-dihydroxy-6(E),8(E),10(E)-eicosatrienoate

: 88020-87-5,88099-35-8,96283-44-2,110771-27-2,127776-70-9,130194-11-5,130194-12-6,135637-50-2,135637-51-3
(+/-)-LTB₃

Guidance literature:: With lithium hydroxide; In 1,2-dimethoxyethane; for 1h; Ambient temperature;
DOI:10.1021/jo00312a031

Reference yield:

: 764-85-2
Nonanoyl chloride

: 88020-87-5,88099-35-8,96283-44-2,110771-27-2,127776-70-9,130194-11-5,130194-12-6,135637-50-2,135637-51-3
(+/-)-LTB₃

Guidance literature:: Multi-step reaction with 3 steps

1: 1) AlCl₃, 2) AlCl₃ / 1) CH₂Cl₂, 0 deg C, 1 h, 2) r.t., 1.5 h

2: 87 percent / NaBH₄ / methanol / 0 °C

3: 46 percent / aq.LiOH / methanol / 0 °C

With lithium hydroxide; sodium tetrahydroborate; aluminium trichloride; In methanol;
DOI:10.1021/jo00021a056

Reference yield:

: 4179-38-8
2-octyl-furan

: 88020-87-5,88099-35-8,96283-44-2,110771-27-2,127776-70-9,130194-11-5,130194-12-6,135637-50-2,135637-51-3
(+/-)-LTB₃

Guidance literature:: Multi-step reaction with 4 steps

1: 2) iodine / 1) dirhodium tetraacetate / 1) 18 h, 2) CH₂Cl₂, RT 6 h

2: 1) aluminium hydride, 2) pyridinium dichromate

3: 1) NaH / 1) DME, 2h, RT, 2) 0.5 h

4: NaBH₄ / H₂O; ethanol / 2 h / Ambient temperature

With aluminium hydride; sodium tetrahydroborate; dipyridinium dichromate; iodine; sodium hydride; dirhodium tetraacetate; In ethanol; water;
DOI:10.1021/jo00312a031