1-(3-{(2Z)-3-methyl-2-[(oxoammonio)methylidene]-2,3-dihydro-1H-imidazol-1-yl}propyl)-3-oxo-1-azoniabicyclo[2.2.2]octane dibromide

Base Information

• Chemical Name: 1-(3-{(2Z)-3-methyl-2-[(oxoammonio)methylidene]-2,3-dihydro-1H-imidazol-1-yl}propyl)-3-oxo-1-azoniabicyclo[2.2.2]octane dibromide
• CAS No.: 208182-95-0
• Molecular Formula: 2Br*C₁₅H₂₄N₄O₂
• Molecular Weight: 452.189
• Mol file: 208182-95-0.mol

Synonyms:

Chemical Property of 1-(3-{(2Z)-3-methyl-2-[(oxoammonio)methylidene]-2,3-dihydro-1H-imidazol-1-yl}propyl)-3-oxo-1-azoniabicyclo[2.2.2]octane dibromide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-{(2Z)-3-methyl-2-[(oxoammonio)methylidene]-2,3-dihydro-1H-imidazol-1-yl}propyl)-3-oxo-1-azoniabicyclo[2.2.2]octane dibromide

There total 2 articles about 1-(3-{(2Z)-3-methyl-2-[(oxoammonio)methylidene]-2,3-dihydro-1H-imidazol-1-yl}propyl)-3-oxo-1-azoniabicyclo[2.2.2]octane dibromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.5%

2-<(hydroxyimino)methyl>-1-methylimidazole (20062-62-8) + 3-oxo-1-(3-bromopropyl)quinuclidinium bromide → 3-oxo-1-[3-(2-hydroxyiminomethyl-3-methyl-1-imidazolio)propyl]-quinuclidinium dibromide (208182-95-0)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1007/s002040050504

Reference yield:

N-methyl-2-imidazolcarboxaldehyde (13750-81-7) → 3-oxo-1-[3-(2-hydroxyiminomethyl-3-methyl-1-imidazolio)propyl]-quinuclidinium dibromide (208182-95-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₂OH

2: 32.5 percent / dimethylformamide / 24 h / 20 °C

With hydroxylamine; In N,N-dimethyl-formamide; 1: Condensation / 2: Substitution;

DOI:10.1007/s002040050504

upstream raw materials:

2-<(hydroxyimino)methyl>-1-methylimidazole

N-methyl-2-imidazolcarboxaldehyde