2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide

Base Information

Chemical Name:2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide
CAS No.:67755-10-6
Molecular Formula:C12H11NO3S
Molecular Weight:249.2856
Hs Code.:
DSSTox Substance ID:DTXSID80218025

Synonyms:3,4-Dihydro-2H,6H-(1,3)thiazino(3,2-b)isoquinolin-6-one 1,1-dioxide;2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide;67755-10-6;6-Oxo-3,4-dihydro-2H,6H-1,3-thiazino(3,2-b)isoquinoline-1,1-dioxide;SCHEMBL11221469;DTXSID80218025;LS-150533

Suppliers and Price of 2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide

Chemical Property:

Vapor Pressure:1.16E-12mmHg at 25°C
Boiling Point:562.1°Cat760mmHg
Flash Point:293.8°C
Density:1.49g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:249.04596439
Heavy Atom Count:17
Complexity:475

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2C(=CC3=CC=CC=C3C2=O)S(=O)(=O)C1

Technology Process of 2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide

There total 4 articles about 2H,6H-(1,3)Thiazino(3,2-b)isoquinolin-6-one, 3,4-dihydro-, 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67755-06-0
3,4-dihydro-2H-[1,3]thiazino[3,2-b]isoquinolin-6-one

: 67755-10-6
1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-[1,3]thiazino[3,2-b]isoquinolin-6-one

Guidance literature:: With dihydrogen peroxide; In acetic acid; at 70 - 80 ℃; for 3h;
DOI:10.1248/cpb.27.2372

Reference yield:

: 67755-50-4
2-(3-mercapto-propyl)-4H-isoquinoline-1,3-dione

: 67755-10-6
1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-[1,3]thiazino[3,2-b]isoquinolin-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: TsOH / 1,2-dichloro-benzene / 0.5 h / 120 °C

2: aq. H₂O₂ / acetic acid / 3 h / 70 - 80 °C

With dihydrogen peroxide; toluene-4-sulfonic acid; In acetic acid; 1,2-dichloro-benzene;
DOI:10.1248/cpb.27.2372

Reference yield:

: 89-51-0
Homophthalic acid

: 67755-10-6
1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-[1,3]thiazino[3,2-b]isoquinolin-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: (i) NaOAc, 1,2-dichloro-benzene, (ii) TsOH

2: aq. H₂O₂ / acetic acid / 3 h / 70 - 80 °C

With dihydrogen peroxide; In acetic acid;
DOI:10.1248/cpb.27.2372