Naphtho[1,2-b]furan-2(3H)-one,3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-, (3S,3aS,5aR,9aR,9bS)-

Base Information

Chemical Name:Naphtho[1,2-b]furan-2(3H)-one,3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-, (3S,3aS,5aR,9aR,9bS)-
CAS No.:10180-76-4
Molecular Formula:C₁₅H₂₂O₂
Molecular Weight:234.338
Hs Code.:

Synonyms:Eudesm-3-en-12-oicacid, 6a-hydroxy-, g-lactone, (11S)- (8CI);Naphtho[1,2-b]furan-2(3H)-one, 3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-,[3S-(3a,3aa,5ab,9aa,9bb)]-; 11b,13-Dihydro-a-cyclocostunolide;Dihydro-a-cyclocostunolide; a-Cyclocostunolide, dihydro-; a-Cyclodihydrocostunolide; a-Santenolide

Suppliers and Price of Naphtho[1,2-b]furan-2(3H)-one,3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-, (3S,3aS,5aR,9aR,9bS)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Naphtho[1,2-b]furan-2(3H)-one,3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-, (3S,3aS,5aR,9aR,9bS)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Naphtho[1,2-b]furan-2(3H)-one,3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-, (3S,3aS,5aR,9aR,9bS)-

There total 1 articles about Naphtho[1,2-b]furan-2(3H)-one,3a,4,5,5a,6,7,9a,9b-octahydro-3,5a,9-trimethyl-, (3S,3aS,5aR,9aR,9bS)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2225-79-8
11βH,13-dihydrocostunolide

: 22387-64-0
dihydro-β-cyclocostunolide

: 23527-07-3
saussurea lactone

: 10180-76-4
(3S,3aS,5aR,9aR,9bS)-3,5a,9-Trimethyl-3a,4,5,5a,6,7,9a,9b-octahydro-3H-naphtho[1,2-b]furan-2-one

Guidance literature:: bis(benzonitrile)palladium(II) dichloride; In toluene; for 24h; Heating;
DOI:10.1016/S0040-4039(97)10775-4

Reference yield:

: 10180-76-4
(3S,3aS,5aR,9aR,9bS)-3,5a,9-Trimethyl-3a,4,5,5a,6,7,9a,9b-octahydro-3H-naphtho[1,2-b]furan-2-one

: 85329-65-3
2-[(1R,6S)-6-(3-[1,3]Dithian-2-yl-propyl)-2,6-dimethyl-cyclohex-2-enylmethoxy]-tetrahydro-pyran

Guidance literature:: Multi-step reaction with 11 steps

1: 58 percent / 1.) LDA, 2.) Mo₅*pyridine*HMPT complex / hexane; tetrahydrofuran / 3 h / -78 °C

2: 885 mg / LiAlH₄ / tetrahydrofuran / 4 h / Heating

3: 98 percent / sodium periodate / tetrahydrofuran; H₂O / 1.2 h / Ambient temperature

4: CH₂Cl₂ / 0.5 h / Ambient temperature

5: activated alumina (Wako) / 2 h

6: 90 percent / LiAlH₄ / diethyl ether / 3 h / Heating

7: 1.) sodium periodate, 2.) sodium borohydride / 1.) THF, 0 deg C, 1 h, 2.) THF, water, 45 min

8: 60 mg / pyridine / 4 °C

9: sodium iodide / acetone / 2.2 h / Heating

10: 82 percent / p-toluenesulfonic acid / tetrahydrofuran

11: 73 percent / diethyl ether / 0 °C

With pyridine; aluminum oxide; sodium tetrahydroborate; sodium periodate; lithium aluminium tetrahydride; Mo₅*pyridine*HMPT; toluene-4-sulfonic acid; sodium iodide; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water; acetone;
DOI:10.1246/bcsj.60.707

Reference yield:

: 10180-76-4
(3S,3aS,5aR,9aR,9bS)-3,5a,9-Trimethyl-3a,4,5,5a,6,7,9a,9b-octahydro-3H-naphtho[1,2-b]furan-2-one

: 85354-55-8
3-((1R,2R)-2-Hydroxymethyl-1,3-dimethyl-cyclohex-3-enyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 7 steps

1: 58 percent / 1.) LDA, 2.) Mo₅*pyridine*HMPT complex / hexane; tetrahydrofuran / 3 h / -78 °C

2: 885 mg / LiAlH₄ / tetrahydrofuran / 4 h / Heating

3: 98 percent / sodium periodate / tetrahydrofuran; H₂O / 1.2 h / Ambient temperature

4: CH₂Cl₂ / 0.5 h / Ambient temperature

5: activated alumina (Wako) / 2 h

6: 90 percent / LiAlH₄ / diethyl ether / 3 h / Heating

7: 1.) sodium periodate, 2.) sodium borohydride / 1.) THF, 0 deg C, 1 h, 2.) THF, water, 45 min

With aluminum oxide; sodium tetrahydroborate; sodium periodate; lithium aluminium tetrahydride; Mo₅*pyridine*HMPT; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water;
DOI:10.1246/bcsj.60.707