Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl-

Base Information

Chemical Name:Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl-
CAS No.:65738-45-6
Molecular Formula:C16H13N
Molecular Weight:219.2811
Hs Code.:
DSSTox Substance ID:DTXSID10215941

Synonyms:65738-45-6;Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl-;6,8-Dimethylcyclopenta[4,5]azepino[2,1,7-cd]pyrrolizine;DTXSID10215941;Cyclopent[4,5]azepino[2,1,7-cd]pyrrolizine,6,8-dimethyl-

Suppliers and Price of Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl-

Chemical Property:

Vapor Pressure:9.88E-09mmHg at 25°C
Boiling Point:462.4°Cat760mmHg
Flash Point:233.5°C
Density:1.18g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:0
Exact Mass:219.104799419
Heavy Atom Count:17
Complexity:511

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C1=CC3=CC=C4N3C(=C2)C=C4)C

Technology Process of Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl-

There total 6 articles about Cyclopent(4,5)azepino(2,1,7-cd)pyrrolizine, 6,8-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 75586-07-1
cyclopenta<4,5>azepino<7,1,2-cd>pyrrolizine-6,8-dicarbaldehyde

: 65738-45-6
6,8-dimethylcyclopenta<4,5>azepino<7,1,2-cd>pyrrolizine

Guidance literature:: With sodium tetrahydroborate; boron trifluoride diethyl etherate; In diethyl ether; diethylene glycol dimethyl ether; 1.) 0 deg C, 30 min, 2.) room temperature, 1 h;
DOI:10.1039/P19800001324

Reference yield:

: 27884-38-4
cyclopenta<4,5>azepino<7,1,2-cd>pyrrolizine

: 65738-45-6
6,8-dimethylcyclopenta<4,5>azepino<7,1,2-cd>pyrrolizine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) POCl₃, 2.) Na₂CO₃ / 1.) 100 deg C, 2 h, 2.) H₂O, 100 deg C, 10 min

2: 67 percent / boron trifluoride-diethyl ether complex, NaBH₄ / bis-(2-methoxy-ethyl) ether; diethyl ether / 1.) 0 deg C, 30 min, 2.) room temperature, 1 h

With sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium carbonate; trichlorophosphate; In diethyl ether; diethylene glycol dimethyl ether;
DOI:10.1039/P19800001324

Reference yield:

: 251-60-5
3H-pyrrolizine

: 65738-45-6
6,8-dimethylcyclopenta<4,5>azepino<7,1,2-cd>pyrrolizine

Guidance literature:: Multi-step reaction with 3 steps

1: 19 percent / NaH / dimethylformamide / 1.) room temperature, 15 min, 2.) 70 deg C, 30 min, 3.) reflux, 15 h

2: 1.) POCl₃, 2.) Na₂CO₃ / 1.) 100 deg C, 2 h, 2.) H₂O, 100 deg C, 10 min

3: 67 percent / boron trifluoride-diethyl ether complex, NaBH₄ / bis-(2-methoxy-ethyl) ether; diethyl ether / 1.) 0 deg C, 30 min, 2.) room temperature, 1 h

With sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium hydride; sodium carbonate; trichlorophosphate; In diethyl ether; diethylene glycol dimethyl ether; N,N-dimethyl-formamide;
DOI:10.1039/P19800001324