3-Hydroxy-24-dimethylaminochol-8(14)-en-15-one

Base Information

Chemical Name:3-Hydroxy-24-dimethylaminochol-8(14)-en-15-one
CAS No.:136320-61-1
Molecular Formula:C₂₆H₄₃NO₂
Molecular Weight:401.633
Hs Code.:
DSSTox Substance ID:DTXSID80929326
Wikidata:Q76009871
Mol file:136320-61-1.mol

Synonyms:3-HDCEO;3-hydroxy-24-dimethylaminochol-8(14)-en-15-one

Suppliers and Price of 3-Hydroxy-24-dimethylaminochol-8(14)-en-15-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Hydroxy-24-dimethylaminochol-8(14)-en-15-one

Chemical Property:

Vapor Pressure:7.23E-13mmHg at 25°C
Boiling Point:517.4°Cat760mmHg
Flash Point:266.7°C
PSA：40.54000
Density:1.06g/cm³
LogP:5.22730
XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:401.329379614
Heavy Atom Count:29
Complexity:682

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCCN(C)C)C1CC(=O)C2=C3CCC4CC(CCC4(C3CCC12C)C)O
Isomeric SMILES:C[C@H](CCCN(C)C)[C@H]1CC(=O)C2=C3CC[C@H]4C[C@H](CC[C@@]4([C@H]3CC[C@]12C)C)O

Technology Process of 3-Hydroxy-24-dimethylaminochol-8(14)-en-15-one

There total 5 articles about 3-Hydroxy-24-dimethylaminochol-8(14)-en-15-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: LiOH*H₂ O

: 136320-63-3
3β-Acetoxy-24-dimethylamino-5α-chol-8(14)-en-15-one

: 136320-61-1
3β-Hydroxy-24-dimethylamino-5α-chol-8(14)-en-15-one

Guidance literature:: In methanol;

Reference yield:

: 136320-63-3
3β-Acetoxy-24-dimethylamino-5α-chol-8(14)-en-15-one

: 136320-61-1
3β-Hydroxy-24-dimethylamino-5α-chol-8(14)-en-15-one

Guidance literature:: With lithium hydroxide; water; In methanol;
DOI:10.1016/0040-4039(91)80590-3

Reference yield:

: 34495-42-6
3β-acetoxy-5α-cholest-8(14)-en-15-one

: 136320-61-1
3β-Hydroxy-24-dimethylamino-5α-chol-8(14)-en-15-one

Guidance literature:: Multi-step reaction with 4 steps

1: 1) H₂O₂, H₂SO₄, 2) triethylamine, methanol / 1) -2 deg C, 3.5 h, 2) THF

2: pyridine / 0 °C

3: dioxane

4: LiOH-H₂O / methanol

With pyridine; methanol; lithium hydroxide; sulfuric acid; water; dihydrogen peroxide; triethylamine; In 1,4-dioxane; methanol;
DOI:10.1016/0040-4039(91)80590-3