4,N-DIHYDROXY-BENZAMIDINE

Base Information

• Chemical Name: 4,N-DIHYDROXY-BENZAMIDINE
• CAS No.: 49787-00-0
• Molecular Formula: C7H8N2O2
• Molecular Weight: 152.153
• Mol file: 49787-00-0.mol

Synonyms:Benzamidoxime,p-hydroxy- (7CI);4-Hydroxy-N-hydroxybenzamidine;4-Hydroxybenzamidoxime;4,N-Dihydroxy-benzamidine;

Chemical Property of 4,N-DIHYDROXY-BENZAMIDINE

Chemical Property:

• Vapor Pressure: 7.82E-05mmHg at 25°C
• Refractive Index: 1.657
• Boiling Point: 390.309 °C at 760 mmHg
• Flash Point: 189.852 °C
• Density: 1.35 g/cm³

Purity/Quality:

97% ^*data from raw suppliers

4-HydroxybenzamidineOxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,N-DIHYDROXY-BENZAMIDINE

There total 4 articles about 4,N-DIHYDROXY-BENZAMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-cyanophenol (767-00-0) → N,4-dihydroxybenzene-1-carboxyimidamide (49787-00-0)

Guidance literature:

With hydroxylamine hydrochloride; sodium hydrogencarbonate; In methanol; for 22h; Reflux;

Reference yield: 98.0%

4-cyanophenol (767-00-0) → N',4-dihydroxybenzamidine (49787-00-0,1219626-47-7)

Guidance literature:

With hydroxylamine hydrochloride; sodium carbonate; In ethanol; for 48h; Reflux;

DOI:10.1016/j.bmcl.2018.09.009

Reference yield:

→ N',4-dihydroxybenzamidine (49787-00-0,1219626-47-7)

Guidance literature:

With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; In ethanol; Reflux;

upstream raw materials:

4-cyanophenol

Downstream raw materials:

4-(5-methyl-1,2,4-oxadiazol-3-yl)phenol

4-(5-pyridin-3-yl-[1,2,4]oxadiazol-3-yl)-phenol

4-[5-(2-chloro-phenyl)-[1,2,4]oxadiazol-3-yl]-phenol

4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-phenol