2-Furanpropanoic acid, beta-hydroxy-alpha-phenyl-, (R*,R*)-(+)-

Base Information

• Chemical Name: 2-Furanpropanoic acid, beta-hydroxy-alpha-phenyl-, (R*,R*)-(+)-
• CAS No.: 119725-47-2
• Molecular Formula: C₁₃H₁₂O₄
• Molecular Weight: 232.236
• DSSTox Substance ID: DTXSID30152561
• Wikidata: Q76280584
• Mol file: 119725-47-2.mol

Synonyms:2-Furanpropanoic acid, beta-hydroxy-alpha-phenyl-, (R*,R*)-(+)-;erytho-(+)-3-(2-Furyl)-3-hydroxy-2-phenylpropanoic acid;(R*,R*)-(+)-beta-Hydroxy-alpha-phenyl-2-furanpropanoic acid;119725-47-2;DTXSID30152561;LS-70545;LS-70546

Chemical Property of 2-Furanpropanoic acid, beta-hydroxy-alpha-phenyl-, (R*,R*)-(+)-

Chemical Property:

• Vapor Pressure: 3.49E-05mmHg at 25°C
• Boiling Point: 339.7°Cat760mmHg
• Flash Point: 159.3°C
• Density: 1.32g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 232.07355886
• Heavy Atom Count: 17
• Complexity: 260

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CO2)O)C(=O)O
• Isomeric SMILES: C1=CC=C(C=C1)[C@H]([C@H](C2=CC=CO2)O)C(=O)O

Technology Process of 2-Furanpropanoic acid, beta-hydroxy-alpha-phenyl-, (R*,R*)-(+)-

There total 15 articles about 2-Furanpropanoic acid, beta-hydroxy-alpha-phenyl-, (R*,R*)-(+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

furfural (98-01-1) → 3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid (72150-09-5,75245-46-4,119725-46-1,119725-47-2,119725-48-3,119725-50-7,119725-51-8,119759-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 1.3 mol/ BuLi, (i-Pr)2NH / 1.) n-C₆H₁₄, abs. THF, 10 min., 2.) n-C₆H₁₄, abs. THF, 1 h

With n-butyllithium; diisopropylamine;

Reference yield:

furfural (98-01-1) → 3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid (72150-09-5,75245-46-4,119725-46-1,119725-47-2,119725-48-3,119725-50-7,119725-51-8,119759-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 1.3 mol/ BuLi, (i-Pr)2NH / 1.) n-C₆H₁₄, abs. THF, 10 min., 2.) n-C₆H₁₄, abs. THF, 1 h

With n-butyllithium; diisopropylamine;

Reference yield:

furfural (98-01-1) → 3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid (72150-09-5,75245-46-4,119725-46-1,119725-47-2,119725-48-3,119725-50-7,119725-51-8,119759-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 1.3 mol/ BuLi, (i-Pr)2NH / 1.) n-C₆H₁₄, abs. THF, 10 min., 2.) n-C₆H₁₄, abs. THF, 1 h

With n-butyllithium; diisopropylamine;

upstream raw materials:

furfural

phenylacetic acid

3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid

3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid

Downstream raw materials:

3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid

3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid

3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid

3-Furan-2-yl-3-hydroxy-2-phenyl-propionic acid