5-Fluoro-7-hydroxymethyl-12-methylbenzanthracene

Base Information

• Chemical Name: 5-Fluoro-7-hydroxymethyl-12-methylbenzanthracene
• CAS No.: 67639-47-8
• Molecular Formula: C20H15FO
• Molecular Weight: 290.3309
• Mol file: 67639-47-8.mol

Synonyms:5-Fluoro-7-hydroxymethyl-12-methylbenzanthracene;

Chemical Property of 5-Fluoro-7-hydroxymethyl-12-methylbenzanthracene

Chemical Property:

• Vapor Pressure: 6.54E-12mmHg at 25°C
• Boiling Point: 526.4°Cat760mmHg
• Flash Point: 325°C
• PSA: 20.23000
• Density: 1.284g/cm³
• LogP: 5.08600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Fluoro-7-hydroxymethyl-12-methylbenzanthracene

There total 4 articles about 5-Fluoro-7-hydroxymethyl-12-methylbenzanthracene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid 5-fluoro-12-methyl-benzo[a]anthracen-7-ylmethyl ester (67639-46-7) → (5-Fluoro-12-methyl-benzo[a]anthracen-7-yl)-methanol (67639-47-8)

Guidance literature:

With sodium hydroxide; In methanol; Heating;

DOI:10.1021/jm00208a013

Reference yield:

7-Chloromethyl-5-fluoro-12-methyl-benzo[a]anthracene (67639-45-6) → (5-Fluoro-12-methyl-benzo[a]anthracen-7-yl)-methanol (67639-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 18-crown-6 / tetrahydrofuran / Heating

2: aq. NaOH / methanol / Heating

With sodium hydroxide; 18-crown-6 ether; In tetrahydrofuran; methanol;

DOI:10.1021/jm00208a013

Reference yield:

3-Fluor-1,2-benzo-anthrachinon (342823-45-4) → (5-Fluoro-12-methyl-benzo[a]anthracen-7-yl)-methanol (67639-47-8)

Guidance literature:

Multi-step reaction with 4 steps

1: benzene; diethyl ether / Heating

2: HCl / ethyl acetate

3: 18-crown-6 / tetrahydrofuran / Heating

4: aq. NaOH / methanol / Heating

With hydrogenchloride; sodium hydroxide; 18-crown-6 ether; In tetrahydrofuran; methanol; diethyl ether; ethyl acetate; benzene;

DOI:10.1021/jm00208a013

upstream raw materials:

Acetic acid 5-fluoro-12-methyl-benzo[a]anthracen-7-ylmethyl ester

7-Chloromethyl-5-fluoro-12-methyl-benzo[a]anthracene

3-Fluor-1,2-benzo-anthrachinon